Sort   by:  
 Page size 
ProteomicsReverse Genetics-Rescued Virulent Feline Calicivirus FCV-BJ616 Recapitulates Systemic Disease and Cytokine Storm in Cats
Feline calicivirus (FCV) is a key pathogen causing upper respiratory diseases and oral ulcers in cats, with significant genetic variability. This study aimed to isolate the FCV-BJ616 strain, investigate its pathogenic mechanisms, and provide insights for developing antibody therapies and broad-spect...
ORGANISM(S): Felis chaus 
2026-02-02 | PXD070016 | Pride
Proteomics. Feline calicivirus Reverse genetics of viruses 
TranscriptomicsRNASeq of African green monkey (Vero) cells infected at a multiplicity of infection (MOI) of 3 with different Zika virus (ZIKV) mutants (American WT, African-like, uORF1-KO and uORF2-PTC1) generated by reverse genetics
Vero cells were infected with the different Zika virus (ZIKV) mutants (American WT, African-like, uORF1-KO and uORF2-PTC1) generated by reverse genetics at MOI:3 to assess their viral transcriptome. Samples were harvested at 24 hours post-infection (h p.i.) by flash-freezing, without cycloheximide p...
ORGANISM(S): Chlorocebus sabaeus 
2024-09-04 | E-MTAB-12968 | biostudies-arrayexpress
TranscriptomicsRiboSeq of African green monkey (Vero) cells infected at a multiplicity of infection (MOI) of 3 with different Zika virus (ZIKV) mutants (American WT, African-like, uORF1-KO and uORF2-PTC1) generated by reverse genetics
Vero cells were infected with the different Zika virus (ZIKV) mutants (American WT, African-like, uORF1-KO and uORF2-PTC1) generated by reverse genetics at MOI:3 to assess their viral transcriptome. Samples were harvested at 24 hours post-infection (h p.i.) by flash-freezing, without cycloheximide p...
ORGANISM(S): Chlorocebus sabaeus 
2024-09-04 | E-MTAB-12969 | biostudies-arrayexpress
TranscriptomicsNovel viruses naturally infecting Caenorhabditis nematodes trigger a small RNA response
C. elegans has served as a laboratory model organism due to its ease of manipulation and the availability of both forward and reverse genetics. In recent years, efforts to study host-pathogen interactions in C. elegans have increased. For example, analysis of infections by bacteria such as Pseudomon...
ORGANISM(S): Caenorhabditis elegans 
2011-01-01 | E-GEOD-21736 | biostudies-arrayexpress
GenomicsReverse genetics of Cache valley and Kairi orthobunyaviruses
Investigation by reverse genetics of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas
PRJEB25770 | ENA
UnknownReverse genetics rescue of sylvatic dengue viruses.
Not available
S-EPMC12282064 | biostudies-literature
TranscriptomicsThe Microbial Detection Array for Detection of Emerging Viruses in Clinical Samples - A Useful Panmicrobial Diagnostic Tool--Array Version 2f
Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each oth...
ORGANISM(S): Dengue virus 1 
2014-03-05 | E-GEOD-55576 | biostudies-arrayexpress
TranscriptomicsThe Microbial Detection Array for Detection of Emerging Viruses in Clinical Samples - A Useful Panmicrobial Diagnostic Tool
Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each oth...
ORGANISM(S): Toscana virus 
2013-11-15 | E-GEOD-52324 | biostudies-arrayexpress
UnknownDevelopment of an entirely plasmid-based reverse genetics system for 12-segmented double-stranded RNA viruses.
Not available
S-EPMC8594578 | biostudies-literature
UnknownHaiku: New paradigm for the reverse genetics of emerging RNA viruses.
Not available
S-EPMC5811033 | biostudies-literature
Sort   by:  
 Page size