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TranscriptomicsTranscriptional profile of B. theta and E. rectale growing in the cecum of mice fed different diets
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Eubacterium rectale 
2010-05-22 | E-GEOD-14709 | biostudies-arrayexpress
TranscriptomicsFixK, a universal regulator of microaerobic growth, controls photosynthesis in Rhodopseudomonas palustris
Facultative phototrophic bacteria are excellent models for analyzing the coordination of major metabolic traits including oxidative phosphorylation, photophosphorylation, carbon dioxide fixation and nitrogen fixation. In Rhodobacter sphaeroides and R. capsulatus, a two-component system called RegBA ...
ORGANISM(S): Rhodopseudomonas palustris 
2010-08-15 | E-GEOD-6742 | biostudies-arrayexpress
MetabolomicsGut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans

The gut microbiota is increasingly recognized for playing a critical role in human health and disease, especially in conferring resistance to both virulent pathogens such as Salmonella, which infects 1.2 million people in the United States every year [1], and opportunistic pathogens like Candida,...

2019-09-20 | MTBLS753 | MetaboLights
TranscriptomicsCharacterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Bacteroides thetaiotaomicron 
2010-05-22 | E-GEOD-14737 | biostudies-arrayexpress
TranscriptomicsEffects of the Fnr homologue AadR on global gene expression
In order to define the AadR regulon we did transcriptome analysis of an aadR in frame-deletion mutant and compared to that of wild type. We found that AadR positively modulated expression of 43 genes, most of which are involved in degradation of aromatic acids under anaerobic conditions. It also act...
ORGANISM(S): Rhodopseudomonas palustris 
2010-12-13 | E-GEOD-19093 | biostudies-arrayexpress
TranscriptomicsRedirection of metabolism for biological hydrogen production
Photosynthetic microbes can produce the clean-burning fuel hydrogen using one of natureâ??s most plentiful resources, sunlight 1,2. Anoxygenic photosynthetic bacteria generate hydrogen and ammonia during a process known as biological nitrogen fixation. This reaction is catalyzed by the enzyme nitrog...
ORGANISM(S): Rhodopseudomonas palustris 
2010-06-10 | E-GEOD-5194 | biostudies-arrayexpress
TranscriptomicsMethanobrevibacter smithii expression profiling
This SuperSeries is composed of the following subset Series: GSE25408: The pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii GSE25535: Expression data from an in vitro growth of Methanobrevibacter smithii PS Refer to individual Series
ORGANISM(S): Methanobrevibacter smithii ATCC 35061 
2011-11-07 | E-GEOD-25537 | biostudies-arrayexpress
TranscriptomicsDissecting the in vivo metabolic potential of two human gut acetogens.
Fermenting microbial communities generate hydrogen: its removal through production of acetate, methane, or hydrogen sulfide modulates the efficiency of energy extraction from available nutrients in many ecosystems. We noted that pathway components for acetogenesis are more abundantly and consistentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-21 | E-GEOD-21906 | biostudies-arrayexpress
TranscriptomicsExpression data from an in vitro growth of Methanobrevibacter smithii PS
RNA-sequencing is a powerful tool for exploring expression profiles of microbial species that does not require the production of a custom genechip. We used microarrays to compare our quantitative RNA-sequencing method to the standard expression quantification methods Methanobrevibacter smithii PS cu...
ORGANISM(S): Methanobrevibacter smithii ATCC 35061 
2011-03-30 | E-GEOD-25535 | biostudies-arrayexpress
TranscriptomicsThe pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii
The human gut microbiota harbors methanogens represented by the dominant archaeon, Methanobrevibacter smithii, a polyphyletic group of acetogens, and sulfate-reducing bacteria. Defining their roles in the H2-economy of the gut has potential therapeutic importance for modulating the efficiency of fe...
ORGANISM(S): Methanobrevibacter smithii 
2011-03-30 | E-GEOD-25408 | biostudies-arrayexpress
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