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TranscriptomicsRapid evolution of phenotypic plasticity and shifting thresholds of genetic assimilation in the nematode Caenorhabditis remanei
Many organisms can acclimate to new environments through phenotypic plasticity, a complex trait that can be heritable, subject to selection, and evolve. However, the rate and genetic basis of plasticity evolution remain largely unknown. We experimentally evolved outbred populations of the nematode C...
ORGANISM(S): Caenorhabditis remanei 
2014-05-04 | E-GEOD-56510 | biostudies-arrayexpress
TranscriptomicsEvolution of phenotypic plasticity and transgenerational effects of heat stress in the nematode Caenorhabditis remanei
Analysis of evolved changes in transcriptional plasticity and parental effects on plasticity induced by mild heat stress in the nematode Caenorhabditis remanei. Results of this study highlight the importance of the broad environmental context of an organism and its influence on phenotypic plasticity...
ORGANISM(S): Caenorhabditis remanei 
2014-10-30 | E-GEOD-62841 | biostudies-arrayexpress
TranscriptomicsTempo-Seq experiment relating to Next Generation Risk Assessment for Occupational Chemical Safety – a Real World Example with Sodium-2-hydroxyethane sulfonate
A dose response and human cell line comparison of transcriptional responses following treatment with the chemical compound Sodium-2-hydroxyethane sulfonate. Gene expression changes were used to estimate the POD - minimum effect concentration when a biological perturbation as estimated by gene exp...
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-14069 | biostudies-arrayexpress
TranscriptomicsPorphyromonas gingivalis 33277 wild-type vs Fur orthologue Har isogenic mutant ECR455
Porphyromonas gingivalis is a major pathogen associated with the microbial biofilm-mediated disease chronic periodontitis. P. gingivalis has an obligate requirement for iron and protoporphyrin IX which it satisfies by transporting heme and iron liberated from the human host. The level of cellular ir...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 
2015-04-01 | E-GEOD-37099 | biostudies-arrayexpress
TranscriptomicsRNA-Seq study of skin and blood samples from prospectively-recruited, deeply-phenotyped discovery and refinement psoriasis cohorts, during targeted treatment with adalimumab or ustekinumab
The Psoriasis Stratification to Optimise Relevant Therapy (PSORT) consortium, prospectively recruited deeply-phenotyped discovery and refinement psoriasis patient cohorts, during the early phase of treatment with two distinct biologics, adalimumab (TNF inhibitor) and ustekinumab (IL-12/23 inhibitor)...
ORGANISM(S): Homo sapiens 
2025-11-19 | E-MTAB-14509 | biostudies-arrayexpress
UnknownEpidemiology of asylum seekers and refugees at the Mexico-US border: a cross-sectional analysis from the migrant settlement camp in Matamoros, Mexico.
Not available
S-EPMC10870647 | biostudies-literature
TranscriptomicsTranscription profiling of Porphyromonas gingivalis wild type and mutant PG1432::ermF to identify genes which have their expression influenced by PG1432
The aim of this experiment is to ascertain which genes have their expression influenced by PG1432. PG1432 encodes a putative sensor histidine kinase which is part of two component signal transduction that was highly up-regulated in P. gingivalis mature biofilm cells. PG1432 was disrupted in P. gingi...
ORGANISM(S): Porphyromonas gingivalis 
2010-01-11 | E-TABM-546 | biostudies-arrayexpress
UnknownConserved cell types with divergent features in human versus mouse cortex.
Not available
S-EPMC6919571 | biostudies-literature
UnknownDefining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement.
Not available
S-EPMC8803367 | biostudies-literature
UnknownEconomic Evaluation of Using Daily Prednisolone versus Placebo at the Time of an Upper Respiratory Tract Infection for the Management of Children with Steroid-Sensitive Nephrotic Syndrome: A Model-Based Analysis.
Not available
S-EPMC9283622 | biostudies-literature
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