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ProteomicsProteomic Analysis and Validation of the RGS14 Signaling Interactome in the Mouse Brain
Regulator of G Protein Signaling 14 (RGS14) is a complex scaffolding protein with an unusual domain structure that allows it to integrate G protein and mitogen-activated protein kinase (MAPK) signaling pathways. RGS14 mRNA and protein are enriched in brain tissue of rodents and primates. In the adul...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-25 | PXD008461 | Pride
Rgs14 Immunoprecipitation Neuroproteomics Interactome 
GenomicsGenetic Deletion of the Inflammatory Bowel Disease -Associated Risk Gene Rgs14 Aggravates Experimental Colitis
Genetic Deletion of the Inflammatory Bowel Disease -Associated Risk Gene Rgs14 Aggravates Experimental Colitis
PRJNA1271053 | ENA
TranscriptomicsGenetic Deletion of the Inflammatory Bowel Disease -Associated Risk Gene Rgs14 Aggravates Experimental Colitis
Regulators of G protein signaling (RGS) deactivate G protein-coupled receptors (GPCRs), one of the most prominent receptor families with diverse functions. Of the twenty RGS, Rgs14 single-nucleotide polymorphism is associated with inflammatory bowel disease. This manuscript describes a novel conditi...
ORGANISM(S): Mus musculus 
2026-04-28 | GSE298744 | GEO
UnknownBiochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A.
Not available
S-EPMC1386029 | biostudies-literature
GenomicsMus musculus strain:C57BL/6
RGS14 KO BAT Transcriptome
PRJNA765403 | ENA
Unknown14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4- signaling complex and RGS14 nuclear localization.
Not available
S-EPMC6153293 | biostudies-literature
UnknownRGS14 limits seizure-induced mitochondrial oxidative stress and pathology in hippocampus.
Not available
S-EPMC10259180 | biostudies-literature
UnknownRGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus.
Not available
S-EPMC9915580 | biostudies-literature
UnknownRegulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector.
Not available
S-EPMC2655719 | biostudies-literature
UnknownHuman genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.
Not available
S-EPMC7949046 | biostudies-literature
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