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ProteomicsXL-MS Analysis of Recombinant GPR158:RGS7:Gb5 Complex in Detergent Micelles
GPR158 is widely expressed in the brain and have been implicated in depression, cognition, mood and several cancers. GPR158 is also involved in retinal photoreceptor signaling along with it involvement in synaptic organization. GPR158 interact with G-protein regulator-RGS7 and brings it to plasma me...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026603 | Pride
Rgs7 Orphan gpcr Gb5 Gpcr-rgs complex Membrane protein complex Gpr158 G-protein coupled receptor Chemical crosslinking 
UnknownInteraction between RGS7 and polycystin.
Not available
S-EPMC26888 | biostudies-literature
UnknownGbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteins.
Not available
S-EPMC26814 | biostudies-literature
UnknownStructure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5.
Not available
S-EPMC8611064 | biostudies-literature
UnknownA RGS7-CaMKII complex drives myocyte-intrinsic and myocyte-extrinsic mechanisms of chemotherapy-induced cardiotoxicity.
Not available
S-EPMC9910480 | biostudies-literature
UnknownSubcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.
Not available
S-EPMC3393828 | biostudies-literature
UnknownArginyltransferase (Ate1) regulates the RGS7 protein level and the sensitivity of light-evoked ON-bipolar responses.
Not available
S-EPMC8087773 | biostudies-literature
UnknownHomeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors.
Not available
S-EPMC6333837 | biostudies-literature
UnknownAssociation of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.
Not available
S-EPMC4060866 | biostudies-literature
UnknownRGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.
Not available
S-EPMC5766496 | biostudies-literature
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