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MetabolomicsRiboflavin produced in the vagina by lactobacilli as symbiotic factor

The human vaginal microbiome, particularly its symbiosis with lactobacilli, plays a key role in maintaining women’s health. While lactic acid-mediated pathogen exclusion is well known, broader metabolic functions of vaginal lactobacilli remain underexplored. In this study, we analyzed the vaginal...

2025-09-26 | MTBLS7389 | MetaboLights
TranscriptomicsTranscriptome profiles of a riboflavin-producing B.subtilis RH33 and wild type B.subtilis 168
The transcriptome profiles of a riboflavin-producing recombinant Bacillus subtilis RH33 and wild type Bacillus subtilis 168 were compared using DNA microarrays to identify the target genes for further enhancing riboflavin production. Transcriptome profiles of a riboflavin-producing B. subtilis RH33 ...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2010-05-05 | E-GEOD-12873 | biostudies-arrayexpress
MetabolomicsGABA regulates IL-1β production in macrophages
Neurotransmitters have been well-documented to determine immune cell fates; however, whether and how γ-amino butyric acid (GABA) shapes the function of innate immune cells is still obscure. Here, we demonstrated that GABA orchestrates macrophage maturation and inflammation. GABA treatment during mac...
2023-01-31 | MTBLS6337 | MetaboLights
MetabolomicsAdaptive laboratory evolution of microbial co-cultures for improved metabolite secretion

Adaptive laboratory evolution has proven highly effective for obtaining microorganisms with enhanced capabilities. Yet, this method is inherently restricted to the traits that are positively linked to cell fitness, such as nutrient utilization. Here, we introduce coevolution of obligatory mutuali...

2021-07-02 | MTBLS2217 | MetaboLights
MetabolomicsOmics-guided global rewiring of yeast metabolism enables high-level production of β-lactoglobulin
This project contains untargeted metabolomic data generated to investigate the metabolic responses of Komagataella phaffii during methanol-free recombinant beta-lactoglobulin production. The study included the bovine beta-lactoglobulin-producing strain B08 and the feline beta-lactoglobulin-producing...
2026-06-05 | MTBLS14680 | MetaboLights
TranscriptomicsArabidopsis transcriptome changes caused by ectopic production of a turtle riboflavin-binding protein
Leaf contents of free riboflavin were modulated by ectopic expression of the turtle gene encoding riboflavin-binding protein (RfBP). Compared to Arabidopsis thaliana (L.) ecotype Col-0 (wild type), REAT (modified type) that constitutive express RfBP had 71%-77% less flavins of free form. We used mi...
ORGANISM(S): Arabidopsis thaliana 
2010-01-01 | E-GEOD-18417 | biostudies-arrayexpress
MetabolomicsAnalysis of flavor formation and metabolite changes during production of buffalo milk Double-Layer Steamed Milk Custard

Metabolomics analysis showed that concentration of free amino acids and short-chain fatty acid lipids were increased in DLSMC, and they were more easily digested and absorbed. Key metabolic pathways, including alanine, aspartate, and glutamate metabolism, starch and sucrose metabolism, and glycer...

2025-08-23 | MTBLS12717 | MetaboLights
UnknownEngineering thermophilic Geobacillus thermoglucosidasius for riboflavin production.
Not available
S-EPMC7936320 | biostudies-literature
UnknownSite-directed mutagenesis of bifunctional riboflavin kinase/FMN adenylyltransferase via CRISPR/Cas9 to enhance riboflavin production.
Not available
S-EPMC11047187 | biostudies-literature
GenomicsPostbiotic potential of newly isolated riboflavin-overproducing Lactiplantibacillus plantarum strains
Postbiotic riboflavin-overproducing Lactiplantibacillus plantarum
PRJEB86045 | ENA
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