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ProteomicsComposition and RNA binding specificity of metazoan RNase MRP
Mechanistic studies have revealed ribonuclease (RNase) MRP, a conserved RNA-based enzyme, is crucial for the maturation of ribosomal RNA in eukaryotes. However, the composition and RNA substrate specificity of this multisubunit ribonucleoprotein complex in higher eukaryotes remain unknown. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-15 | PXD061658 | Pride
Nepro Ribonuclease (rnase) mrp C18orf21 Ip-ms 
TranscriptomicsRNAi profiling by array of human HEp-2 cells with siRNA-mediated depletion of RNase MRP protein components
To identify mRNA substrates for the human RNase MRP complex, we examined the effects of siRNA-mediated depletion of RNase MRP (and RNase P) on the transcriptome of HEp-2 cells. The expression of two RNase MRP protein components, hPop1 and Rpp40, was knocked-down and after 48 hours mRNA was isolated ...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-TABM-981 | biostudies-arrayexpress
GenomicsComposition and RNA binding specificity of metazoan RNase MRP
Composition and RNA binding specificity of metazoan RNase MRP
PRJNA1231220 | ENA
OtherComposition and RNA binding specificity of metazoan RNase MRP
Ribonuclease (RNase) MRP is a conserved RNA-based enzyme that is essential for maturation of ribosomal RNA (rRNA) in eukaryotes. However, the composition and RNA substrate specificity of this multisubunit ribonucleoprotein complex in higher eukaryotes remain a mystery. Here, we identify NEPRO and C1...
ORGANISM(S): Mus musculus 
2025-08-05 | GSE290995 | GEO
UnknownIdentification of Two Elusive Human Ribonuclease MRP-Specific Protein Components.
Not available
S-EPMC11785048 | biostudies-literature
UnknownInteractions between subunits of Saccharomyces cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture.
Not available
S-EPMC2095792 | biostudies-literature
UnknownModular architecture of eukaryotic RNase P and RNase MRP revealed by electron microscopy.
Not available
S-EPMC3326328 | biostudies-literature
UnknownComposition and RNA binding specificity of metazoan RNase MRP.
Not available
S-EPMC11870539 | biostudies-literature
UnknownComposition and RNA binding specificity of metazoan RNase MRP.
Not available
S-EPMC12390755 | biostudies-literature
UnknownIdentification of RMP24 and RMP64, human ribonuclease MRP-specific protein components.
Not available
S-EPMC12406990 | biostudies-literature
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