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PARP15 is a mono-ADP-ribosyltransferase with unknown functions. Its evolutionary relationship with PARP14 suggests roles in antiviral defense; its ability to modify RNA and localization to stress granules point to functions in the regulation of translation. PARP15 also modifies itself and other prot...
ORGANISM(S): Homo sapiens (Human) 
2025-10-02 | PXD061403 | Pride
Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation (RIP-Seq in vivo)
Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation (RIP-Seq in vitro)
Tyrosine phosphorylation is key for signal transduction from exogeneous stimuli, including the defence against pathogenic microbes. Pathogens have acquired mechanisms to subvert protein phosphorylation as a means to control host immune responses and facilitate invasion and dissemination. The bacteri...
ORGANISM(S): Homo sapiens (Human) 
2018-03-16 | PXD008533 | Pride
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