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TranscriptomicsTranscription profiling by array of Salmonella typhimurium SL1344 derived multidrug resistant mutant
Transcriptome of a ciprofloxacin selected multidrug resistant mutant derived from Salmonella Typhimurium SL1344
ORGANISM(S): Salmonella typhimurium 
2010-12-04 | E-MEXP-2696 | biostudies-arrayexpress
ProteomicsINPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH
In this study, we describe new patients suffering from INPP5K mutations and hereby expand the mutational and clinical spectrum of the underlying disease. Pathogenicity of a new INPP5K missense mutation has been functionally confirmed. In addition, we systematically addressed the need to identify com...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD009272 | Pride
L-serine Inpp5k Bip Phgdh Sil1 
TranscriptomicsA long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation
RNA-seq was performed in biological replicates (2 mice per group) of wild-type and lincRNA-EPS-/- BMDMs at 0, 2, and 6 hours after LPS treatment (100 ng/ml). RNA-seq libraries were prepared as described (Heyer et al., 2015). Briefly, ribosomal RNA (rRNA) was depleted using the Ribozero rRNA removal ...
ORGANISM(S): Mus musculus 
2016-07-29 | E-MTAB-4088 | biostudies-arrayexpress
UnknownFurosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
Not available
S-EPMC4305226 | biostudies-literature
UnknownCoFish: co-designing citizen science between fishers and scientists to monitor the phosphorus distribution across two lake Geneva basins.
Not available
S-EPMC12720463 | biostudies-literature
TranscriptomicsTranscriptional profile of carcinoma-stem-like cells (CSC) extracted from a primary ovarian cancer cell line
A population of non-adherent cells with stem-like characteristics (OVA-BS4 spheres) has been isolated from a primary human epithelial ovarian cancer (EOC) cell line (OVA-BS4) under selective conditions. OVA-BS4 spheres were characterized for their pharmacological properties and their molecular profi...
ORGANISM(S): Homo sapiens 
2018-01-15 | E-MTAB-4799 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human eessential thrombocythemia megakaryocytes versus normal megakaryocytes
Normal donors BM CD34+ cells were differentiated in thrombopoietin-treated liquid suspension cultures. Briefly, CD34+ cells (80,000 /mL) were resuspended in a serum-free medium in the presence of 100 ng/mL of human recombinant thrombopoietin (TPO; Genzyme, Boston, MA). Every 3 days, viable cells wer...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-997 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human essential Thrombocythemia (ET) vs normal (baseline) megakaryocytes
Essential Thrombocythemia (ET) patients, as well as normal donors BM CD34+ cells were differentiated in thrombopoietin-treated liquid suspension cultures. Briefly, CD34+ cells (80,000 /mL) were resuspended in a serum-free medium in the presence of 100 ng/mL of human recombinant thrombopoietin (TPO; ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-567 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of the effects of the novel mithramycin analogue DIG-MSK on human A2780 ovarian carcinoma cells
The effects of demycarosyl-3D-M-NM-2-D-digitoxosyl-mithramycin SK (DIG-MSK; EC-8042), a novel analogue of the antitumor antibiotic mithramycin A, on gene transcription were examined in human A2780 ovarian carcinoma cells. DIG-MSK down-regulated a different set of genes depending on the drug concentr...
ORGANISM(S): Homo sapiens 
2014-08-13 | E-GEOD-46926 | biostudies-arrayexpress
UnknownHydrocortisone malabsorption due to polyethylene glycols (Macrogol 3350) in a girl with congenital adrenal insufficiency.
Not available
S-EPMC4422474 | biostudies-literature
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