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TranscriptomicsTranscription profiling time series of zebrafish hearts treated with dioxin (TCDD)
For analysis of gene expression changes in the zebrafish larvae heart in response to TCDD exposure, three replicate samples of heart tissue were collected at 73, 74, 76 and 84 hours post fertilization from larvae exposed to 1 ng/ml TCDD or vehicle from 72 - 73 hours post fertilization. For analysis ...
ORGANISM(S): Danio rerio 
2006-06-29 | E-MEXP-758 | biostudies-arrayexpress
ProteomicsProteomic profile of Campylobacter jejuni 11168 during in vitro growth in the presence or absence of penicillin
The proteomic makeup of three biological replicates of cells incubated for 24 h in MHB (control) or three biological replicates of cells incubated for 24 h in MHB containing 100 x MIC of penicillin G was analysed. The control or penicillin-treated cultures were stained with RSG and sorted using FACS...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168-BN148 
2020-10-20 | PXD021418 | Pride
Proteomics Penicillin Campylobacter jejuni 
UnknownAssessing the ocular surface microbiome in severe ocular surface diseases.
Not available
S-EPMC7905829 | biostudies-literature
TranscriptomicsImpact of ectopic expression of SNAIL2, ZEB2, ZEB1 or TWIST1 on BRAF-target genes in the murine melanocytic melan-a cell line
We have demonstrated that the oncogenic activation of B-RAF (using a truncated delta-BRAF-ER version inducible with tamoxifen) in the melan-a melanocyte cell line triggers the activation of Zeb1 and Twist1 at the expanse of Zeb2 and Snail2. Enforced maintenance of Zeb2 or Snail2 expression reduces t...
ORGANISM(S): Mus musculus 
2013-10-29 | E-GEOD-39030 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
ProteomicsPeptidomic analysis of pancreatic neurodendocrine tumours (Glucagonoma)
A peptidomic analysis of plasma from patients with well characterised pancreatic neuroendocrine tumours (PNET) was performed. A nano LC-MS analysis identified a number of peptides from the glucagon gene, which were idenfiried in a previous case study using multiple immunoassays. Peptides to other pr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082880 | MassIVE
TranscriptomicsVirus-Induced Airway Disease in Mice (C57BL/6J, d49)
Analysis of gene expression in lungs of C57BL/6J mice that develop chronic airway disease phenotypes after a single Sendai virus infection, compared with mice treated with UV-inactivated virus. Keywords: disease state analysis Whole lung RNA was analyzed from 3 mice per condition per time point 49 d...
ORGANISM(S): Mus musculus 
2013-08-08 | E-GEOD-49603 | biostudies-arrayexpress
TranscriptomicsCritical role for the DNA receptor AIM2 in stem-cell proliferation and cancer
Colorectal cancer is a leading cause of cancer-related deaths. Mutations in the innate immune receptor AIM2 are frequently identified in patients with colorectal cancer, but how AIM2 modulates colonic tumorigenesis is unknown. Here, we found that Aim2-deficient mice were hypersusceptible to colonic ...
ORGANISM(S): Mus musculus 
2015-07-15 | E-GEOD-69436 | biostudies-arrayexpress
GenomicsGenome-Wide Analysis of Hypodiploid Acute Lymphoblastic Leukemia

Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive form of leukemia characterized by multiple whole chromosomal losses and very poor outcome. Here we report an integrative genomic analysis that identifies multiple subtypes of hypodiploid ALL characterized by variation in the degree o...

phs000341.v1.p1 | EGA
UnknownMinimal manifestation status and prednisone withdrawal in the MGTX trial.
Not available
S-EPMC7455358 | biostudies-literature
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