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ProteomicsProteomic profile of Campylobacter jejuni 11168 during in vitro growth in the presence or absence of penicillin
The proteomic makeup of three biological replicates of cells incubated for 24 h in MHB (control) or three biological replicates of cells incubated for 24 h in MHB containing 100 x MIC of penicillin G was analysed. The control or penicillin-treated cultures were stained with RSG and sorted using FACS...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168-BN148 
2020-10-20 | PXD021418 | Pride
Proteomics Penicillin Campylobacter jejuni 
TranscriptomicsTime-course gene expression data from deletion strains of Penicillium chrysogenum
In filamentous fungi, secondary metabolism is often linked with developmental processes such as conidiation. In this study we analyzed the link between secondary metabolism and conidiation in the main industrial producer of the β-lactam antibiotic penicillin, the ascomycete Penicillium chrysogenum. ...
ORGANISM(S): Penicillium chrysogenum 
2011-01-04 | E-GEOD-23326 | biostudies-arrayexpress
TranscriptomicsTime-course gene expression data from deletion strains of Penicillium chrysogenum
The recent discovery of a velvet complex containing several regulators of secondary metabolism in the model fungus Aspergillus nidulans raises the question whether similar type complexes direct fungal development in genera other than Aspergillus. Penicillium chrysogenum is the industrial producer of...
ORGANISM(S): Penicillium chrysogenum 
2010-06-17 | E-GEOD-18585 | biostudies-arrayexpress
TranscriptomicsExpression data of Streptococcus pneumoniae against penicillin
The increasing rate of penicillin resistance in S. pneumoniae in the early 1970s has resulted in therapeutic challenges and has prompted the need for alternative therapy in the management of pneumococcal infections. The development of penicillin resistance has been documented to be as a result of al...
ORGANISM(S): Streptococcus pneumoniae 
2010-05-13 | E-GEOD-21709 | biostudies-arrayexpress
GenomicsNon-vaccine type penicillin nonsusceptible pneumococcus
Non-vaccine type penicillin nonsusceptible pneumococcus
PRJEB13827 | ENA
ProteomicsFirst penicillin-binding protein occupancy patterns for 15 β-lactams and β-lactamase inhibitors in Mycobacterium abscessus
Mycobacterium abscessus (Mab) causes serious infections that often require over 18 months of antibiotic combination therapy. With β lactam antibiotics being safe, double β-lactam and β-lactam/β-lactamase inhibitor combinations are of interest for improving treatment of Mab infections and minimizing ...
ORGANISM(S): Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) 
2020-11-24 | PXD022644 | Pride
Penicillin-binding proteins Beta-lactams Cell wall biosynthesis Pona2 Pona1 Pbpa Mycobacterium abscessus 
TranscriptomicsExpression data of Streptococcus pneumoniae against penicillin
The increasing rate of penicillin resistance in S. pneumoniae in the early 1970s has resulted in therapeutic challenges and has prompted the need for alternative therapy in the management of pneumococcal infections. The development of penicillin resistance has been documented to be as a result of al...
ORGANISM(S): Streptococcus pneumoniae TIGR4 Streptococcus pneumoniae 
2010-05-13 | GSE21709 | GEO
TranscriptomicsImpact of Velvet complex on transcriptome and penicillin G production in glucose-limited chemostat cultures of a beta-lactam high-producing Penicillium chrysogenum strain
The multi-component global regulator Velvet complex has been identified as a key regulator of secondary metabolite production in Aspergillus and Penicillium species. Previous work indicated a massive impact of PcvelA and PclaeA deletions, two key components of the Velvet complex, on penicillin produ...
ORGANISM(S): Penicillium chrysogenum 
2011-12-06 | E-GEOD-31633 | biostudies-arrayexpress
ProteomicsCombine in silico target fishing, Comparative proteomics analysis and in vitro assays to identify antibacterial effects of a TCM (the leaves of Strobilanthes cusia Kuntze) against the Penicillin resistant Streptococcus pneumoniae
The anti-bacterial mechanism of the leaves of Strobilanthes cusia Kuntze against the Penicillin-resistant Streptococcus pneumoniae were analyzed by the comparative proteomics
ORGANISM(S): Streptococcus Pneumoniae 23f 
2022-12-18 | PXD038886 |
TranscriptomicsGenomic Loss of Penicillin-Binding Protein 3 in Burkholderia pseudomallei Confers Clinical Resistance to Ceftazidime
Array-CGH analysis and Burkholderia pseudomallei isolates pre and post ceftazidime relapse. Genomic DNA from both the parental strains and variant strains were labeled with Cy3 or Cy5 fluorescent dyes and hybridized onto a customized microarray with probes designed from the reference Bp K96243 genom...
ORGANISM(S): Burkholderia pseudomallei 
2011-10-06 | E-GEOD-25832 | biostudies-arrayexpress
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