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TranscriptomicsA microRNA-based primary tumor site classification of liver core biopsies
To develop a classifier based on microRNAs for primary tumor site identification of liver core biopsies and to explore the influence of surrounding normal liver tissue on classification. Tissue samples from 333 patients, corresponding to one of the following ten assay classes, were obtained from arc...
ORGANISM(S): Homo sapiens 
2013-10-19 | E-GEOD-51429 | biostudies-arrayexpress
UnknownEffects of neck-exercise and health promotion on headache outcomes in office workers: secondary analysis of the NEXpro stepped wedge cluster randomised controlled trial.
Not available
S-EPMC11817237 | biostudies-literature
TranscriptomicsBcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c
During neocortical development, neurons undergo polarization, oriented migration, and layer type-specific differentiation. The transcriptional programs underlying these processes are not completely understood. Here we show that the transcription factor Bcl11a regulates polarity and migration of uppe...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-52827 | biostudies-arrayexpress
MetabolomicsMapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC–MS
The metabolism of the parasite Trypanosoma brucei has been the focus of numerous studies since the 1940s. Recently it was shown, using metabolomics coupled with heavy-atom isotope labelled glucose, that the metabolism of the bloodstream form parasite is more complex than previously thought. The pres...
2019-06-24 | MTBLS624 | MetaboLights
TranscriptomicsSingle-cell RNA-seq of Pdgfra+/Sca1+/Cd31- mouse cardiac cells
Adult mice hearts contain a population of resident mesenchymal stem cell (MSC)-like cells called cardiac colony forming units-fibroblast (cCFU-F). The cCFU-F are housed in a population of non-muscle cardiac cells that are Pdgfra+/Sca1+/Cd31- (S+P+ fraction). The goal of this experiment was to profil...
ORGANISM(S): Mus musculus 
2019-03-28 | E-MTAB-7365 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of mouse cardiac interstitial cells 3 & 7 days after sham or myocardial infarction injury
The aims of the experiment were to profile the cell types in the adult mouse cardiac interstitium (non-myocyte cells) and how they respond to myocardial infarction injury. Adult, male, Pdgfra +/GFP mice were subject to either a myocardial infarction or sham injury, with cells isolated from cardiac v...
ORGANISM(S): Mus musculus 
2019-03-28 | E-MTAB-7376 | biostudies-arrayexpress
TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-07-07 | E-GEOD-17179 | biostudies-arrayexpress
ProteomicsAnalysis of the effect of ClpC1 directed antibiotics on ClpC1, ClpC2 and ClpC3 protein levels.
Ecumicin and Cyclomarin A (CymA) are known antimicrobial compounds that target the NTD of ClpC1. In proteomics analysis of compound treated M. smegmatis, two novel protein, ClpC2 and ClpC3, have been identified as strong interactors of those compounds in addition to ClpC1. In this study we used PRM ...
ORGANISM(S): Mycolicibacterium Smegmatis 
PXD037198 | panorama
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
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