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TranscriptomicsA high-resolution single-cell multiomic atlas of the human fetal lung - scRNA / GEX / VDJ
We obtained human embryonic and fetal lungs from 5-22 pcw for scRNAseq and scATACseq analysis. To focus on epithelial differentiation and region specialization, we deeply sampled 15, 18, 20 and 22 pcw lungs and separated proximal and distal regions while leaving lungs at 5, 6, 9 and 11 pcw intact. T...
ORGANISM(S): Homo sapiens 
2022-01-27 | E-MTAB-11278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli high-cell-density recombinant and wild-type
The transcriptome profiles for wild-type (plasmid-free) and recombinant (plasmid-bearing) Escherichia coli during well-controlled synchronized high-cell-density fed-batch cultures were analyzed by DNA microarrays. It was observed that the growth phase significantly affected the transcriptome profile...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17505 | biostudies-arrayexpress
UnknownVitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study.
Not available
S-EPMC8728359 | biostudies-literature
TranscriptomicsDistinct and Overlapping Gene Regulatory Networks in BMP- and HDAC-Controlled Cell Fate Determination in the Embryonic Forebrain
Both bone morphogenetic proteins (BMPs) and histone deacetylases (HDACs) have previously been established to play a role in the development of the three major cell types of the central nervous system: neurons, astrocytes, and oligodendrocytes. We have previously established a connection between thes...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-31792 | biostudies-arrayexpress
TranscriptomicsH. salinarum NRC-1 vs VNG2099C knockout
To investigate the contribution of ribonucleases to post-transcriptional regulation of mRNA levels, we examined the fitness consequences and gene expression changes of ribonuclease mutants in the extreme halophilic archaeon Halobacterium salinarum NRC-1. H. salinarum NRC-1 is known to use a large re...
ORGANISM(S): Halobacterium sp. NRC-1 
2014-03-03 | E-GEOD-45988 | biostudies-arrayexpress
ProteomicsIdentification of cerebrospinal fluid biomarkers for parkinsonism using a proteomics approach
The aim of our study was to investigate cerebrospinal fluid (CSF) tryptic peptide profiles as potential diagnostic biomarkers for the discrimination of parkinsonian disorders. CSF samples were collected from individuals with parkinsonism, who had an uncertain diagnosis at the time of inclusion and w...
ORGANISM(S): Homo Sapiens 
2022-01-10 | PXD028888 | panorama
UnknownFirst-in-human phase I trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein, SL-172154 in patients with platinum-resistant ovarian cancer.
Not available
S-EPMC11749819 | biostudies-literature
TranscriptomicsImmune cells direct epithelial maturation during early human lung development
The adult human lung harbours a significant proportion of immune cells, which are known to play a crucial role in both normal lung homeostasis and pathogenesis. In this work, we collected CD45-enriched human lung cells from 6 to 22 week post conception (pcw) and built a single-cell transcriptome and...
ORGANISM(S): Homo sapiens 
2022-12-09 | E-MTAB-11528 | biostudies-arrayexpress
UnknownLow-fat Dietary Pattern and Pancreatic Cancer Risk in the Women's Health Initiative Dietary Modification Randomized Controlled Trial.
Not available
S-EPMC6059156 | biostudies-literature
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
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