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Unknownmda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis.
Not available
S-EPMC5313338 | biostudies-literature
Unknownmda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.
Not available
S-EPMC4911293 | biostudies-literature
UnknownDifferential roles for CLA-1L and UNC-10 in endosomal maturation and peptide release at <i>C. elegans</i> synapses impacting lifespan.
Not available
S-EPMC12823496 | biostudies-literature
UnknownEnhanced Cancer Therapy Using an Engineered Designer Cytokine Alone and in Combination With an Immune Checkpoint Inhibitor.
Not available
S-EPMC8988683 | biostudies-literature
TranscriptomicsOligoarray comparative genomic hybridisation-mediated mapping of suppressors of an essential receptor tyrosine kinase generated in a deletion-biased mutagenesis screen
We have used oligoarray comparative genomic hybridization (aCGH) to identify novel suppressors generated in a UV-TMP based suppressor screen. This approach is suitable for detecting single gene mutations as well as copy number variations. Keywords: C.elegans Suppressor screen array CGH [1] 2 test s...
ORGANISM(S): Caenorhabditis elegans 
2012-07-12 | E-GEOD-15224 | biostudies-arrayexpress
TranscriptomicsPneumococcal conjugate vaccination at birth induces robust recall responses at 9 months of age.
The objective of this study was to compare recall responses to vaccine antigens at 3 months and 9 months of age in infants who were vaccinated at birth or at 1 month. PBMC were obtained at 9 months of age from infants who were vaccinated at birth (n=25) or 1 month (n=25). The PBMC were cultured in t...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-25263 | biostudies-arrayexpress
TranscriptomicsCopy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans
Background: Copy number variation is an important component of genetic variation in higher eukaryotes. The extent of natural copy number variation in C. elegans is unknown outside of 2 highly divergent wild isolates and the canonical N2 Bristol strain. Results: We have used array comparative genomic...
ORGANISM(S): Caenorhabditis elegans 
2010-05-17 | E-GEOD-19440 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 3 day old C. elegans RILs exposes for 240 minutes to 0 mM or 400 mM ethanol
In this experiment we evaluate the transcriptional responses of C. elegans to 0 mM and 400 mM ethanol after 240 minutes by mapping expression quantitative trait loci. We used 70 mpRILs and their parental lines (JU1511, JU1926, JU1931, and JU1941). Animals were 3 day old when exposure and tissue coll...
ORGANISM(S): Caenorhabditis elegans 
2026-06-30 | E-MTAB-15535 | biostudies-arrayexpress
TranscriptomicsCopy number variation in the genomes of Caenorhabditis elegans end-to-end fusion strains
End-to-end chromosome fusions that occur in the context of telomerase deficiency can trigger genomic duplications. These duplications are suggested to arise via Breakage-Fusion-Bridge cycles. To test this hypothesis, we examined end-to-end fusions isolated from C. elegans telomere replication mutant...
ORGANISM(S): Caenorhabditis elegans 
2011-01-21 | E-GEOD-26691 | biostudies-arrayexpress
UnknownExploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.
Not available
S-EPMC7004330 | biostudies-literature
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