Richter C C - OmicsDI

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Unknown (2170)
Transcriptomics (107)
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Organisms

Homo sapiens (129)
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Disease

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Technology Type

Mass Spectrometry (89)
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Gel-based experiment (7)
Mass spectrometry (6)
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SWATH MS (5)
Top-down proteomics (4)
Affinity proteomics (3)
Mass spectrometry assay (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
DiaPASEF (2)
Illumina HiSeq 2000, HumanMethylation450k Bead Chip - Genome Studio, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2000, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
NMR spectroscopy (1)
HDMSE (1)
Immunopeptidomics (1)
Olink affinity proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (7)
Illumina HiSeq 1500 (6)
NextSeq 500 (5)
NextSeq 550 (4)
Liquid Chromatography MS - negative - reverse phase (4)
Liquid Chromatography MS - positive - reverse phase (4)
NextSeq 2000 (2)
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Illumina HiSeq 4000 (2)
6520A Quadrupole Time-of-Flight LC/MS (2)
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2012 (17)
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2014 (12)
2010 (12)
2016 (10)
2013 (9)
2015 (7)
2018 (7)
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2019 (5)
2017 (5)
2007 (4)
2008 (2)
2005 (1)
2003 (1)

UNIPROT ID/AC

O75293 (1)
O95257 (1)
P04637 (1)
P24522 (1)
P38936 (1)
Q00987 (1)
Q13315 (1)
Q16539 (1)

CHEBI ID

CHEBI:15903 (2)
CHEBI:16919 (2)
CHEBI:17191 (2)
CHEBI:30769 (2)
CHEBI:16991 (1)
CHEBI:26523 (1)
CHEBI:29108 (1)
CHEBI:1148 (1)
CHEBI:116314 (1)
CHEBI:132542 (1)
CHEBI:132579 (1)
CHEBI:134242 (1)
CHEBI:134487 (1)
CHEBI:134587 (1)
CHEBI:137552 (1)
CHEBI:137590 (1)
CHEBI:140940 (1)
CHEBI:140946 (1)
CHEBI:140951 (1)
CHEBI:15366 (1)
CHEBI:15422 (1)
CHEBI:15428 (1)
CHEBI:15603 (1)
CHEBI:156118 (1)
CHEBI:15713 (1)
CHEBI:15721 (1)
CHEBI:15727 (1)
CHEBI:15729 (1)
CHEBI:15741 (1)
CHEBI:15746 (1)

Metabolite Name

3-Methylcrotonylglycine (3)
Richter (3)
Taurine (3)
(+/-)-Tryptophan (2)
(1Xi,3Xi)-1,2,3,4-Tetrahydro-1-Methyl-Beta-Carboline-3-Carboxylic Acid (2)
10,11-Dihydro-20-Trihydroxy-Leukotriene B4 (2)
20-Carboxy-Ltb4 (2)
20-Hydroxy-Leukotriene B4 (2)
3,4-Dihydroxyhydrocinnamic Acid (2)
3-Hydroxydodecanedioic Acid (2)
3-Methylsuberic Acid (2)
4-Dodecylbenzenesulfonic Acid (2)
4-Hydroxy-3-Prenylbenzoic Acid Glucoside (2)
4-Hydroxybenzaldehyde (2)
4-Nitrophenol (2)
5'-N-Ethylcarboxamidoadenosine (2)
5-Hydroxyindole-3-Acetic Acid (2)
5-Methoxytryptophan (2)
6A,12A-Dihydroxylithocholic Acid (2)
8-Azaguanine (2)
Abeado (2)
Acetylhomoserine (2)
Acorafloxacin (2)
Alaptide (2)
Alpha-D-Glucose (2)
Annomuricatin A (2)
Aspartame (2)
Azelaic Acid (2)
Capecitabine (2)
Cinncassiol A (2)

First Public Date

2020 (2)
2016 (1)

Modelling Approach

Ordinary differential equation model (2)

Lab affiliation

The University of Sydney (6)
The University of Melbourne (3)
Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (2)
The University of Sydney, Australia (2)
Universität Greifswald Institut für Pharmazie, AG Pharmazeutische Biotechnologie Greifswald, Germany (2)
2Oncode Institute and Department of Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands. (1)
AG Evolutionäre Genetik der Pflanzen Fak. V - Institut für Biologie und Umweltwissenschaften (IBU) Carl von Ossietzky Universität Oldenburg Carl von Ossietzky-Str. 9-11 26111 Oldenburg (1)
AGH Univeristy (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Bioanalytical Mass spectrometry, Max Planck Institute For Biophysical Chemistry, Goettingen, Germany (1)
Cancer Proteomics Lab Department of Molecular Cell Biology Weizmann Institute of Science, Rehovot (1)
Cell Biophysics, Nencki Institute, Warsaw, Poland (1)
Cell Cycle Control and Carcinogenesis, F045, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany (1)
Center for Cancer Research, Massachusetts General Hospital, Boston MA, USA;Department of Chemistry and Chemical Biology, Harvard University, Cambridge MA, USA. (1)
Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul-Wittsack-Str. 10, 68163 Mannheim, Germany (1)
Center for Molecular Biology of Heidelberg University (ZMBH) (1)
Center for Plant Molecular Biology (ZMBP) University of Tübingen Tübingen, Germany (1)
Chair of the Department of Functional Genomics Institute of Functional Genomics, University of Regensburg, Am Biopark 9, 93053 Regensburg, Germany ( lab head ) (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)
Competence Center Functional Genomics, Junior Research Group Pathoproteomics, University of Greifswald, 17489 Greifswald, Germany (1)
DZNE - German Center for Neurodegenerative Diseases Munich Neuroproteomics Feodor-Lynen Str. 17 D-81377 Munich Germany (1)
Department Medical Biochemistry, University of Gothenburg, Gothenburg, Sweden (1)
Department of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany. (1)
Department of Arctic and Marine Biology, UiT The Arctic University of Norway, Norway (1)
Department of Biomedicine, University of Bergen, Norway (1)
Department of Chemistry, Durham University, Stockton Rd, DH1 3LE, Durham, United Kingdom (1)
Department of Gene Regulation Friedrich Miescher Institute for Biomedical Research (1)
Department of Gene Regulation Friedrich Miescher Institutefor Biomedical Research (1)
Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Düsseldorf, Germany (1)
Department of Molecular Medicine, University of Padua, via A. Gabelli 63, 35121 Padua, Italy (1)

IsPrivate

False (2)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)
Not available (1)

Study type

Transcription profiling by array (55)
RNA-seq of coding RNA (22)
ChIP-seq (9)
RNA-seq of coding RNA from single cells (5)
Unknown experiment type (4)
Comparative genomic hybridization by array (4)
Methylation profiling by high throughput sequencing (4)
Cell line - High-throughput sequencing (3)
ChIP-chip by array (2)
Methylation profiling by array (2)
RNA-seq of total RNA (2)
Baseline (1)
ChIP-chip by tiling array (1)
One-color microarray (1)
Plant - High-throughput sequencing (1)
Cell line - One-color microarray (1)
RNAi profiling by array (1)
ATAC-seq (1)
DNA-seq (1)
CUT&RUN (1)

Release Date

2022 (279)
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2020 (204)
2019 (125)
2018 (115)
2016 (89)
2015 (86)
2017 (85)
2014 (74)
2011 (63)
2012 (62)
2013 (55)
2010 (37)
2009 (33)
2026 (30)
2008 (20)
2007 (12)
2004 (6)
2003 (5)
2002 (5)
2005 (4)
2006 (3)
2001 (3)
2000 (2)
1996 (1)

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Aberrant c-AMP signalling in richter syndrome revealed by single-cell transcriptome and 3D chromatin analysis.

Not available

S-EPMC11756191 | biostudies-literature

GNPS - Lomaiviticin C - purified

LCMS analysis of LC-purified lomaiviticin C - Reference: Kersten, R.D., Lane, A.L., Nett, M., Richter, T.K., Duggan, B.M., Dorrestein, P.C., Moore, B.S. Bioactivity-Guided Genome Mining Reveals the Lomaiviticin Biosynthetic Gene Cluster in Salinispora tropica. Chembiochem 14, 955-962 (2013).

ORGANISM(S): Salinispora Tropica Cnb440

2014-05-22 | MSV000078665 | GNPS

GNPS - Lomaiviticin A C D E - purified

LCMS run of LC-purified lomaiviticins A, C, D & E - Reference: Kersten, R.D., Lane, A.L., Nett, M., Richter, T.K., Duggan, B.M., Dorrestein, P.C., Moore, B.S. Bioactivity-Guided Genome Mining Reveals the Lomaiviticin Biosynthetic Gene Cluster in Salinispora tropica. Chembiochem 14, 955-962 (2013).

ORGANISM(S): Salinispora Tropica Cnb440

2014-05-22 | MSV000078664 | GNPS

C/EBPÎ± induces highly efficient macrophage transdifferentiation of selected B-lymphoma /leukemia cell lines and impairs their tumorigenicity

Earlier work demonstrated that the transcription factor C/EBPÎ± can convert immature and mature murine B lineage cells into functional macrophages. Testing >20 human lymphoma and leukemia B-cell lines, we found that most can be transdifferentiated at least partially into macrophage-like cells, provi...

ORGANISM(S): Homo sapiens

2013-03-14 | E-GEOD-44700 | biostudies-arrayexpress

How we treat Richter syndrome.

Not available

S-EPMC3954047 | biostudies-literature

PRC2 in Ewing tumors

We found the PRC2 component EZH2 to be upregulated by the pathognomonic fusion oncogene EWS-FLI1 in Ewing tumors and mesenchymal stem cells (Richter GH et al., Proc Natl Acad Sci U S A. 2009;106:5324-9). Downregulation of EZH2 by RNA interference in Ewing tumor cell lines suppressed oncogenic transf...

ORGANISM(S): Homo sapiens

2009-04-29 | E-GEOD-15757 | biostudies-arrayexpress

Proteomic analysis of L6 myoblasts treated with C-terminal transgelin peptides

To investigate bioactivity of peptides identified in human plasma, we treated L6 myoblasts in vitro with a synthetic C-terminal peptide from TAGLN spanning amino acids 179-200, or a synthetic C-terminal peptide from TAGLN2 spanning amino acids 178-199 (1 µg/mL; 7 days), and compared the treatments t...

ORGANISM(S): Rattus norvegicus (Rat)

2017-11-21 | PXD007176 | Pride

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.

Not available

S-EPMC4836368 | biostudies-literature

Richter Syndrome: From Molecular Pathogenesis to Druggable Targets.

Not available

S-EPMC9563287 | biostudies-literature

A chromatin-modifying function of JNK during stem cell differentiation

Signaling mediates cellular responses to extracellular stimuli. The c-Jun NH2-terminal kinase (JNK) pathway exemplifies one sub-group of Mitogen-activated protein (MAP) kinases, which besides established functions in stress response, also contributes to developmental processes by an unknown mechanis...

ORGANISM(S): Mus musculus

2011-12-18 | E-GEOD-25532 | biostudies-arrayexpress

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