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GenomicsGenomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells (ChIP-seq)
Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional plasticity and potential. Here we report the dynami...
ORGANISM(S): Mus musculus 
2011-06-21 | E-GEOD-27827 | biostudies-arrayexpress
GenomicsA comparative epigenomics approach reveals REST as a mediator of Polycomb reprogramming during neuronal differentiation
Transcription factors (TFs) in concert with chromatin pathways stably reset transcriptional programs during differentiation. Yet we know little how local sites of chromatin reprogramming are specified and how the estimated 3000 TF encoded in mammalian genomes contribute to chromatin dynamics. To ide...
ORGANISM(S): Mus musculus 
2012-09-04 | E-GEOD-27148 | biostudies-arrayexpress
TranscriptomicsGenomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells (RNA-seq)
Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional plasticity and potential. Here we report the dynami...
ORGANISM(S): Mus musculus 
2011-06-21 | E-GEOD-27843 | biostudies-arrayexpress
ProteomicsApolipoprotein A-IV is induced by high-fat diets and mediates positive effects on glucose and lipid metabolism
Low-carbohydrate, high-fat diets under eucaloric conditions are associated with several health-beneficial metabolic effects in humans, particularly in the liver. We recently observed that apolipoprotein A-IV (apoA-IV), a highly abundant apolipoprotein, was among the most upregulated proteins in the ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055918 | Pride
Liver Apoa4 
Transcriptomics17b-Trenbolone study
We investigated the genomic transcriptional response of female fathead minnows (Pimephales promelas) to an acute (4 day) exposure to 0.1 or 1.0 µg/L of, 17β-trenbolone (TB), the active metabolite of an anabolic androgenic steroid used as a growth promoter in cattle and a contaminant of concern in ...
ORGANISM(S): Pimephales promelas 
2010-05-14 | E-GEOD-12904 | biostudies-arrayexpress
UnknownPeriprocedural anticoagulation during left atrial ablation: interrupted and uninterrupted vitamin K-antagonists or uninterrupted novel anticoagulants.
Not available
S-EPMC5924498 | biostudies-literature
TranscriptomicsTranscription profiling of human late passage hiPSCs (pluripotent stem cells)
Detailed analysis comparing induced pluripotent stem cells revealed functional gene expression differences to hESCs that are changed with long term passaging. We used microarrays to detail the changes that are made throughout passaging to hiPSC lines. Experiment Overall Design: hiPSC lines were harv...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-16654 | biostudies-arrayexpress
UnknownDigital PCR-based quantification of miR-181a in the cerebrospinal fluid aids patient stratification in pediatric acute lymphoblastic leukemia.
Not available
S-EPMC11574027 | biostudies-literature
GenomicsEtiology matters - Comparing Genomic DNA Methylation Patterns in Three Rat Models of Acquired Epilepsy (Amygdala stimulation – MBD-seq)
Explore DNA methylation in focal amygdala stimulation model of epilepsy and its relationship to gene expression. Examination of methylation changes in stimulated rats compared to sham operated animals in focal amygdala stimulation model of epilepsy.
ORGANISM(S): Rattus norvegicus 
2016-09-06 | E-GEOD-75400 | biostudies-arrayexpress
TranscriptomicsEtiology matters - Comparing Genomic DNA Methylation Patterns in Three Rat Models of Acquired Epilepsy (Amygdala stimulation – mRNA-seq)
Explore DNA methylation in focal amygdala stimulation model of epilepsy and its relationship to gene expression. Examination of expression changes in stimulated rats compared to sham operated animals in focal amygdala stimulation model of epilpesy.
ORGANISM(S): Rattus norvegicus 
2016-09-06 | E-GEOD-75402 | biostudies-arrayexpress
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