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Comparison of gene expression between the virulent Rickettsia rickettsii R strain and avirulent Rickettsia rickettsii Iowa. Keywords: virulent vs avirulent Virulent Rickettsia rickettsii R strain in triplicate was compared to avirulent Rickettsia rickettsii Iowa in triplicate
ORGANISM(S): Rickettsia rickettsii 
Strains of R. rickettsii, the agent of Rocky Mountain spotted fever, differ greatly in the severity of the disease caused. The genetic differences responsible for this disparity are only now being uncovered. An avirulent, laboratory adapted strain of R. rickettsii fails to proteolytically process se...
ORGANISM(S): Rickettsia rickettsii str. 'Sheila Smith' Rickettsia rickettsii str. Iowa 
2023-07-06 | PXD041355 | Pride
Rickettsiae are strict obligate intracellular pathogens that alternate between arthropod and mammalian hosts in a zoonotic cycle. Typically, pathogenic bacteria that cycle between environmental sources and mammalian hosts adapt to the respective environments by coordinately regulating gene expressio...
ORGANISM(S): Rickettsia rickettsii 
Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa
Different types of cell death, including apoptosis, play an important role in the immune defense of arthropods, as infected cells are eliminated, preventing the dissemination of the infectious agent throughout the animal body. The apoptosis can be triggered by two main pathways: the intrinsic or mit...
ORGANISM(S): Rickettsia rickettsii 
2021-09-09 | PXD017942 | Pride
Rickettsia rickettsii str. Hauke Genome sequencing
Rickettsia rickettsii str. Arizona Genome sequencing
Rickettsia rickettsii str. Brazil Genome sequencing
Rickettsia rickettsii str. Hino Genome sequencing
Rickettsia rickettsii str. Colombia Genome sequencing
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