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Type I interferons (IFNs) are consequential cytokines in antibacterial defense. Whether and how bacterial pathogens inhibit innate immune receptor-driven type I IFN expression remains mostly unknown. By screening a library of enterohemorrhagic Escherichia coli (EHEC) mutants, we uncovered EhaF, an ...
ORGANISM(S): Mus musculus (Mouse) Escherichia coli 
2023-04-13 | PXD041070 | Pride
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis
ORGANISM(S): Bartonella Henselae Str. Houston-1 
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis. Wild type.
ORGANISM(S): Bartonella Henselae Str. Houston-1 
The intracellular bacterium Orientia tsutsugamushi relies on the microtubule cytoskeleton and the motor protein dynein to traffic to the perinuclear region within infected cells. However, it remains unclear how the bacterium is coupled to the dynein machinery and how transport is regulated. Here, we...
ORGANISM(S): Homo sapiens (Human) 
2025-06-03 | PXD064516 | Pride
Antibodies are key to the clearance of Bartonella bacteremia, but the mechanisms and targets of protective antibodies are unknown and bacterial evasion strategies remain elusive. We studied experimental Bartonella taylorii infection of mice, its natural host, and investigated protective immune respo...
ORGANISM(S): Bartonella henselae 
2022-08-12 | PXD028783 | Pride
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