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Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the endoplasmic reticulum membrane and acquires ...

2023-01-06 | MTBLS6076 | MetaboLights
Ixodes species ticks are competent vectors of tick-borne viruses including tick-borne encephalitis and Powassan encephalitis.  Tick saliva has been shown to facilitate and enhance viral infection.  This likely occurs by saliva-mediated modulation of host responses into patterns favorable for viral i...
ORGANISM(S): Mus musculus 
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcr...
ORGANISM(S): Ixodes scapularis 
We examined gene expression induced by Rhipicephalus microplus bites on host skin of tick-resistant and tick-susceptible breeds of bovines, Nelore and Holstein respectively, when they underwent a primary infestation.
ORGANISM(S): Bos taurus 
Subolesin is an evolutionary conserved protein that was recently discovered in Ixodes scapularis as a tick protective antigen and has a role in tick blood digestion, reproduction and development. In other organisms, subolesin orthologs may be involved in the control of developmental processes. Beca...
ORGANISM(S): Ixodes scapularis 
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcr...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) 
2015-10-05 | PXD002181 | Pride
Understanding the molecular basis of how the tick adapts to feed on different animal hosts is central to understanding tick and tick-borne disease (TBD) epidemiology. Tick adaptation to feed on vertebrate hosts is regulated by tick secretion of multiple tick saliva proteins (TSPs) and other molecule...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) Amblyomma americanum 
2022-02-28 | PXD007712 | Pride
Tick proteins within a fraction from medium pressure liquid chromatography were identified as potential chemoattractants for Borrelia burgdorferi. The proteins in two replicate fractions were identified using LC-MS/MS.
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) 
2021-09-08 | PXD011273 | Pride
Organophosphate resistant and susceptible tick larvae from laboratory strains of the southern cattle tick, Rhipicephalus (Boophilus) microplus were exposed to low doses of the organophosphate (OP) acaricide, coumaphos. Serial Analysis of Gene Expression (SAGE) was used to analyze differential gene ...
ORGANISM(S): Rhipicephalus microplus 
Tick infestations by Rhipicephalus microplus, the cattle tick, cause enormous losses to health and animal production. Ticks induce immune response in their hosts; therefore their immunobiological control is feasible. The available anti-tick vaccines display variable efficacy and short-lived, encoura...
ORGANISM(S): Bos taurus 
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