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ProteomicsMetaproteome analysis of different soil types
Metaproteome analysis of a forest soil and a potting soil. Different protein extraction methods were compared to investigate protein extraction efficiency and compatibility with sample downstream processing.
ORGANISM(S): unidentified environmental samples 
2015-03-26 | PRD000542 | Pride
ProteomicsMetaproteomics of Lobaria pulmonaria
Not available
ORGANISM(S): Lobaria pulmonaria 
2011-05-05 | PRD000387 | Pride
ProteomicsMetaproteomics of leaf-litter decomposer communities
Not available
2012-07-16 | PRD000425 | Pride
ProteomicsHolistic proteome analyses of heart samples from GHR-deficient (GHR-KO) pigs
A proteomics analysis of heart samples from GH receptor deficient (GHR-KO) pigs has been performed. This animal model is unique to study consequences of lacking GH actions. In this study, we used LC-MS/MS to capture alterations in the heart proteome of this clinically relevant large animal model.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-12-01 | PXD019852 | Pride
Growth hormone  laron syndrome  heart  pig model  proteomics 
ProteomicsProteomic changes of the liver in the absence of growth hormone (GH) actions
The liver is a central target organ of growth hormone (GH), which stimulates the synthesis of insulin-like growth factor 1 (IGF1) and affects multiple biochemical pathways. A systematic multi-omics analysis of GH actions in the liver has not been performed. GH receptor (GHR) deficiency is a unique m...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-03-30 | PXD017671 | Pride
Liver  growth hormone  laron syndrome  pig model  proteomics 
TranscriptomicsRNA sequencing analysis of DAF-16 target gene expression when math-33 function is genetically inactivated
In this study we have investigated the effect of loss of math-33 activity on DAF-16-mediated target gene regulation in C. elegans under conditions of reduced Insulin/IGF-1 signaling (IIS). Using whole nematode RNA sequencing experiments we found that the daf-2(e1370)-mediated induction and repressio...
ORGANISM(S): Caenorhabditis elegans 
2016-06-22 | E-GEOD-70117 | biostudies-arrayexpress
ProteomicsHeart proteome in Cox10 depending on Opa1 processing
Mitochondrial fusion and fission accompany adaptive responses to stress and altered metabolic demands. Inner membrane fusion and cristae morphogenesis depends on Optic Atrophy 1 (Opa1), which is expressed in different isoforms and is cleaved from a membrane-bound, long to a soluble, short form. Here...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD048804 | Pride
Heart Cox10 Opa1 
UnknownPhase 1b study of enzalutamide plus CC-115, a dual mTORC1/2 and DNA-PK inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC).
Not available
S-EPMC10781677 | biostudies-literature
UnknownRESPONDER - diagnosis of pathological complete response by vacuum-assisted biopsy after neoadjuvant chemotherapy in breast Cancer - a multicenter, confirmative, one-armed, intra-individually-controlled, open, diagnostic trial.
Not available
S-EPMC6109284 | biostudies-literature
TranscriptomicsAntibody repertoire RNA-seq throughout key stages of mouse B-cell development (pre-B-cells, naive B cells, plasma cells)
We sought to investigate the extent of genetic and antigen-driven predetermination of antibody repertoires throughout B-cell development (pre-B cells, naive B cells, plasma cells). To this end, we used (i) an inbred model organism (mouse, C57BL/6J) to quantify genetic predetermination and (ii) cohor...
ORGANISM(S): Mus musculus 
2017-03-28 | E-MTAB-5349 | biostudies-arrayexpress
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