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Wood, or secondary xylem, is the product of xylogenesis, a developmental process that begins with the proliferation of cambial derivatives and ends with mature xylem fibers and vessels with lignified secondary cell walls. Fully mature xylem has undergone a series of cellular processes, including ...

2020-09-01 | MTBLS1796 | MetaboLights

Wood, or secondary xylem, is the product of xylogenesis, a developmental process that begins with the proliferation of cambial derivatives and ends with mature xylem fibers and vessels with lignified secondary cell walls. Fully mature xylem has undergone a series of cellular processes, including ...

2020-09-01 | MTBLS1797 | MetaboLights

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights

To better understand the effect of different LC-MS setups on metabolite detection, five laboratories analyzed 1298 standard compounds obtained from the MetaSci metabolite standard library, classified as 'Human Endosome' (HE), 'Food Exposome' (FE), 'Chemical Exposome' (CE), 'Microbiota Exposome' (...

2026-04-24 | MTBLS14343 | MetaboLights
Not available
ORGANISM(S): Plasmodium falciparum;Homo sapiens 
Intracellular pathogen infection leads to proteotoxic stress in host organisms. Previously we described a physiological program in the nematode C. elegans called the Intracellular Pathogen Response (IPR), which promotes resistance to proteotoxic stress and appears to be distinct from canonical prote...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2020-02-07 | MSV000084936 | MassIVE

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights
To help understand the cellular function of a gene the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by th...
ORGANISM(S): Homo Sapiens 
2020-05-28 | PXD016193 | panorama
Ubiquitin and ubiquitin-like proteins (UBLs) are directed to targets by cascades of E1, E2, and E3 enzymes. The largest ubiquitin E3 subclass consists of cullin-RING ligases (CRLs), which contain one each of several cullins (CUL1, -2, -3, -4, or -5) and RING proteins (RBX1 or -2). CRLs are activated...
ORGANISM(S): Mus musculus 
Ring-infected erythrocytes are the predominant asexual stage in the peripheral circulation but are rarely investigated in the context of acquired immunity against Plasmodium falciparum malaria. Here we compare antibody-dependent phagocytosis of ring-infected parasite cultures in samples from a contr...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-08-11 | PXD033964 | Pride
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