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ProteomicsThe UAS domain of UBXN7 interacts with RNF111 RING domain
In this study we performed 2 interactomes. To identify interactants of RNF111 that are dependent of the RING domain, we performed qualitative interactome comparison of HEK-293 cells transfected with GFP, GFP-RNF111-wt or GFP-RNF11-C933A mutated in its RING domain. This led to the identification of U...
ORGANISM(S): Homo sapiens (Human) 
2023-04-07 | PXD034999 | Pride
Hek293 cells Ubxn7 Rnf111 
ProteomicsIdentification of RNF111 substrates by integrative ubiquitome and proteome analysis
In the present work, we sought to identify exhaustively the endogenous substrates ubiquitinated and degraded by the E3 ubiquitin ligase RNF111 in presence of TGF-β signaling by performing label free quantitative proteomics after enrichment of ubiquitinated proteins (ubiquitome) in parental U2OS cell...
ORGANISM(S): Homo sapiens (Human) 
2021-11-17 | PXD025890 | Pride
Ubiquitome E3 ubiquitin ligase Tgf-beta Rnf111 
GenomicsEffect of Rnf111 S254A mutant on chromatin accessibility
Effect of Rnf111 S254A mutant on chromatin accessibility
PRJNA1246106 | ENA
TranscriptomicsMultiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control
The RING domain protein Arkadia/RNF111 is a ubiquitin ligase in the transforming growth factor beta (TGFβ) pathway. We previously identified Arkadia as a small ubiquitin-like modifier (SUMO)-binding protein with clustered SUMO-interacting motifs (SIMs) that together form a SUMO-binding domain (SBD)....
ORGANISM(S): Mus musculus 
2015-02-11 | E-GEOD-65796 | biostudies-arrayexpress
GenomicsEffect of Rnf111 S254D mutant on gene expression at intestine tissues
Effect of Rnf111 S254D mutant on gene expression at intestine tissues
PRJNA1244856 | ENA
GenomicsEffect of Rnf111 S254D mutant on gene expression on embryo at E7.5
Effect of Rnf111 S254D mutant on gene expression on embryo at E7.5
PRJNA1244726 | ENA
GenomicsDeleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
PRJNA1062707 | ENA
GenomicsEffect of Rnf111 S254A mutant on chromatin accessibility
ATAC analysis of DNAs extracted from cells of wild type or Rnf111 S254A
ORGANISM(S): Homo sapiens 
2025-04-08 | GSE293722 | GEO
TranscriptomicsDeleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It represents a significant detriment to female fertility. However, the known POI-causative genes currently account for only a fraction of cases. To elucidate ...
ORGANISM(S): Mus musculus 
2024-06-11 | GSE252791 | GEO
UnknownRNF111-facilitated neddylation potentiates cGAS-mediated antiviral innate immune response.
Not available
S-EPMC7959372 | biostudies-literature
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