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GenomicsActD timecourse in HeLa cells, HeLa RNF219 KO cells, HeLa RNF219 KO cells overexpressing 3xFLAG-SBP-RNF219-WT or 3xFLAG-SBP-RNF219-mut
ActD timecourse in HeLa cells, HeLa RNF219 KO cells, HeLa RNF219 KO cells overexpressing 3xFLAG-SBP-RNF219-WT or 3xFLAG-SBP-RNF219-mut
PRJNA721707 | ENA
GenomicsFunctional characterization of RNF219
Functional characterization of RNF219
PRJNA610788 | ENA
TranscriptomicsActD timecourse in HeLa cells, HeLa RNF219 KO cells, HeLa RNF219 KO cells overexpressing 3xFLAG-SBP-RNF219-WT or 3xFLAG-SBP-RNF219-mut
The evolutionarily conserved CCR4-NOT complex acts as a central player in the control of mRNA turnover and mediates accelerated mRNA degradation upon histone deacetylase (HDAC) inhibition. Here, we explored acetylation-induced changes in the composition of the CCR4-NOT complex by purification of the...
ORGANISM(S): Homo sapiens 
2021-10-27 | GSE172019 | GEO
TranscriptomicsFunctional characterization of RNF219
In this study, we analyzed the function of RNF219 in gene expression control by RNA-Seq analyses in mouse embryonic stem cells after RNF219 knockdown.
ORGANISM(S): Mus musculus 
2021-03-05 | GSE146511 | GEO
UnknownRNF219 interacts with CCR4-NOT in regulating stem cell differentiation.
Not available
S-EPMC7883825 | biostudies-literature
UnknownThe E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity.
Not available
S-EPMC12582992 | biostudies-literature
ProteomicsIdentification of acetylation-regulated interactors of the human CCR4-NOT complex
The evolutionarily conserved CCR4-NOT complex acts as a central player in the control of mRNA turnover and mediates accelerated mRNA degradation upon histone deacetylase (HDAC) inhibition. Here, we explored acetylation-induced changes in the composition of the CCR4-NOT complex by purification of the...
ORGANISM(S): Homo sapiens (Human) 
2021-12-15 | PXD027237 | Pride
Rnf219 Mrna turnover Protein acetylation Deadenylation E3 ubiquitin ligase Ccr4-not complex 
UnknownRNF219 regulates CCR4-NOT function in mRNA translation and deadenylation.
Not available
S-EPMC9166816 | biostudies-literature
UnknownRNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Not available
S-EPMC8660800 | biostudies-literature
TranscriptomicsGenes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq]
Purpose : to decipher the role a newly identified protein, RNF219, we performed a knock down of this protein and try to determine how it affect the global mRNA expression of the cells.
ORGANISM(S): Homo sapiens 
2019-11-15 | GSE95442 | GEO
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