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TranscriptomicsSF-1 and RNF31 knockdown and forskolin treatment
The human adrenocortical carcinoma cell line NCI-H295R treated with siRNA targeting SF-1 or RNF31 with luciferase-targeting siRNA as control. Combined with forskolin treatment.
ORGANISM(S): Homo sapiens 
2012-02-01 | E-MEXP-3259 | biostudies-arrayexpress
ProteomicsRNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
Tumor escape mechanisms for immunotherapy include deficiencies in antigen presentation, diminishing adaptive CD8+ T cell antitumor activity. Although innate NK cells are triggered by loss of MHC class I, their response is often inadequate. To increase tumor susceptibility to both innate and adaptive...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029489 | Pride
Rnf31 Tnf Ap 
UnknownTaraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer.
Not available
S-EPMC8024285 | biostudies-literature
GenomicsFunction of RNF31 in the Triple Negative Breast Cancer
Function of RNF31 in the Triple Negative Breast Cancer
PRJNA903795 | ENA
GenomicsGenome wide expression change by RNF31 knocking down in MCF-7 cells
Genome wide expression change by RNF31 knocking down in MCF-7 cells
PRJNA693877 | ENA
TranscriptomicsThe gene expression change of RNF31 depletion in MCF-7 cells
RNF31 is atypical E3 ligase, which is highly expressed in human breast cancers. In order to understand the effect of RNF31 depletion effect in breast cancers, we knocked down the expression of RNF31 in MCF-7 cells. We aim to find the significantly changed pathways and cell biology behavior.
ORGANISM(S): Homo sapiens 
2014-02-06 | GSE46010 | GEO
UnknownRBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31.
Not available
S-EPMC9307510 | biostudies-literature
GenomicsRNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
PRJNA773728 | ENA
UnknownIdentification and molecular analysis of RNF31 Q622H germline polymorphism.
Not available
S-EPMC9533369 | biostudies-literature
TranscriptomicsGenome wide expression change by RNF31 knocking down in MCF-7 cells
We aim to the investigate the role of RNF31 in breast cancer progression. MCF-7 cells were used as the model and RNF31 was silenced by siRNA.
ORGANISM(S): Homo sapiens 
2021-04-30 | GSE165289 | GEO
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