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ProteomicsRNF41 regulation of the dendritic cell receptor Clec9A
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8+ T cell immune responses. This study investigates the role of E3 ubiquitin ligase RNF41 in Clec9A-mediated ubiquitination, and Clec9A-interactions.
ORGANISM(S): Homo sapiens (Human) 
2020-11-27 | PXD018926 | Pride
Rnf41 E3 ubiquitin ligase Ubiquitination Clec9a 
ProteomicsOrthogonal interactome profiling of RNF41
Ring finger protein 41 (RNF41) is an E3 ubiquitin ligase involved in the ubiquitination and degradation of many proteins such as ErbB3 receptors, BRUCE and parkin. Next to this, RNF41 regulates the intracellular trafficking of certain JAK-2 associated cytokine receptors by ubiquitinating and suppres...
ORGANISM(S): Homo sapiens (Human) 
2018-03-26 | PXD007794 | Pride
Human ap-ms viortrap bioid 
TranscriptomicsRnf41 is associated with anxiety like behavior, major depression and beta carboline induced seizure
The molecular etiology of invididual differences in complex behavior traits and susceptibility to psychiatric illness remains incomplete. Using an unbiased genetic approach in a mouse model, Quantitative Trait Loci (QTL) influencing anxiety-like behaviors and beta-carboline-induced seizure vulnerabi...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8641 | biostudies-arrayexpress
UnknownRNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration.
Not available
S-EPMC10712730 | biostudies-literature
TranscriptomicsRnf41 is associated with anxiety like behavior, major depression and beta carboline induced seizure
The molecular etiology of invididual differences in complex behavior traits and susceptibility to psychiatric illness remains incomplete. Using an unbiased genetic approach in a mouse model, Quantitative Trait Loci (QTL) influencing anxiety-like behaviors and beta-carboline-induced seizure vulnerabi...
ORGANISM(S): Mus musculus 
2008-06-30 | GSE8641 | GEO
UnknownRNF41 interacts with the VPS52 subunit of the GARP and EARP complexes.
Not available
S-EPMC5439944 | biostudies-literature
Unknownm6A-mediated silencing of RNF41 by METTL3/YTHDC1 disrupts autophagy to drive intervertebral disc degeneration.
Not available
S-EPMC12580432 | biostudies-literature
UnknownRNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.
Not available
S-EPMC7710356 | biostudies-literature
Unknownm6A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation.
Not available
S-EPMC9709059 | biostudies-literature
UnknownReciprocal regulatory balance within the CLEC16A-RNF41 mitophagy complex depends on an intrinsically disordered protein region.
Not available
S-EPMC10066562 | biostudies-literature
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