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TranscriptomicsRIP-chip analysis of the C. elegans GLD-2 and RNP-8 protein
C. elegans GLD-2 forms an active PAP with multiple RNA-binding partners to regulate diverse aspects of germline and early embryonic development. One GLD-2 partner, RNP-8, was previously shown to influence oocyte fate specification. To identify transcripts selectively associated with both GLD-2 and R...
ORGANISM(S): Caenorhabditis elegans 
2010-09-21 | E-GEOD-23843 | biostudies-arrayexpress
ProteomicsXL-MS of 5S RNP preribosomal complexes
The 5S RNP is assembled from its three components (5S rRNA, Rpl5/uL18, and Rpl11/uL5) before being incorporated into the pre-60S subunit. However, when ribosome synthesis is disturbed, a free 5S RNP can enter the MDM2–p53 pathway to regulate cell cycle and apoptotic signaling. Here we reconstitute a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-06-13 | PXD040087 | Pride
5s rnp Cryo-em Mdm2 
ProteomicsirCLIP-RNP reveals patterns of dynamic protein associations on RNA
RNA binding proteins (RBPs) interact with RNA targets to control an array of processes, including RNA splicing, stability, transport, and translation1-3. Dysfunctional RNA-RBP interactions contribute to pathogenesis of a plethora of human diseases1,4,5, underscoring the need for a greater understand...
ORGANISM(S): Homo sapiens (Human) 
2025-01-28 | PXD053494 | Pride
Mass spectrometry Ms Crisslinking immunoprecipitation Rna binding proteins Clip Rbp 
TranscriptomicsHITS-CLIP of cytoplasmic SLBP RNP
UV cross-linking and immunoprecipiatation with high throughput sequencing of cytoplasmic SLBP RNP Polyclonal α-SLBP antibody was used to immunoprecipitate UV-crosslinked SLBP RNP from cytoplasmic HeLa lysates. Mock immunoprecipitation were also performed and serve as a negative control.
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-61958 | biostudies-arrayexpress
ProteomicsProteomic Analysis of fly brain cytoplasmic RNP granules containing the lncRNA mimi
In neurons, mRNAs and associated RNA-binding proteins assemble into ribonucleoprotein (RNP) granules essential to regulate mRNA trafficking, local translation, and turnover. Dysregulation of RNA-protein condensation can disturb synaptic plasticity. We report that the novel lncRNA mimi is a constitut...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-12 | PXD034453 | Pride
Rnp granules  fly brain  neurons  lncrna mimi Fne  rbp9 Drosophila  relative ibaq  quantitative proteomics 
GenomicsGranulocytes stimulated by Recombinant N protein (rNP)
Granulocytes stimulated by Recombinant N protein (rNP)
PRJNA1469543 | ENA
GenomicsDetection of RNAs binding to Vg1 RNP
Detection of RNAs binding to Vg1 RNP
PRJNA647395 | ENA
GenomicsNK cell stimulated by Recombinant N protein (rNP)
NK cell stimulated by Recombinant N protein (rNP)
PRJNA1470638 | ENA
TranscriptomicsTranscription profiling of mouse polysome vs RNP fractions from testis obtained from prepuberttal and adult animals to investigate post transcriptional control mechanisms in gametes
Gametes rely heavily on post-transcriptional control mechanisms to regulate their differentiation. In eggs, the storage and selective temporal activation of maternal mRNAs is essential for normal development. In the male, transcription ceases during spermiogenesis necessitating the post-transcriptio...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-4711 | biostudies-arrayexpress
TranscriptomicsRIP-seq of polyribosomal SLBP RNP
UV cross-linking and immunoprecipiatation with high throughput sequencing of cytoplasmic SLBP RNP Polyclonal α-SLBP antibody was used to immunoprecipitate SLBP RNP from polyribosomal fractions of HeLa S3 lysates. Mock immunoprecipitation were also performed and serve as a negative control.
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-62076 | biostudies-arrayexpress
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