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TranscriptomicsDSIF and RNA polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes
Histone deacetylase Rpd3 is part of two distinct complexes: the large (Rpd3L) and small (Rpd3S) complexes. While Rpd3L targets specific promoters for gene repression, Rpd3S is recruited to ORFs to deacetylate histones in the wake of RNA polymerase II, to prevent cryptic initiation within genes. Meth...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-28 | E-GEOD-22636 | biostudies-arrayexpress
TranscriptomicsA Universal RNA Polymerase II CTD Cycle Is Orchestrated by Complex Interplays Between Kinase, Phosphatase and Isomerase Enzymes Along Genes
Transcription by RNA polymerase II (RNAPII) is coupled to mRNA processing and chromatin modifications via the C-terminal domain (CTD) of its largest subunit, consisting of multiple repeats of the heptapeptide YSPTSPS. Pioneering studies showed that CTD serines are differentially phosphorylated along...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-01 | E-GEOD-29403 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of Arabidopsis thaliana cells treated with RN1 and 2,4-D
A PSB-D wild type Arabidopsis thaliana cell culture (Arabidopsis Biological Resource Center stock: CCL84840) was grown after subculturing for one week and divided into separate 10 mL samples for 24 h. Samples were then treated with 50 µM RubNeddin1 (RN1, Chembridge ID 6389186), 2,4-D, or an equal vo...
ORGANISM(S): Arabidopsis thaliana 
2021-08-03 | E-MTAB-7761 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptation genome wide location of H2A.Z binding sites in yeast yeast
genome wide location of H2A.Z binding sites in yeast Saccharomyces cerevisiae. Nucleosome density controled with H2B ChIP. Hybridization control ChIP H2AZ/H2AZ and H2A/H2B.
ORGANISM(S): Saccharomyces cerevisiae 
2005-12-31 | E-MEXP-396 | biostudies-arrayexpress
TranscriptomicsTranscriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin
In this study, we analyzed the transcriptome of a highly differentiated mouse clonal CCD principal cell line (mpkCCD(cl4)) and the changes in the transcriptome induced by aldosterone and vasopressin. Serial analysis of gene expression (SAGE) was performed on untreated cells and on cells treated with...
ORGANISM(S): Mus musculus 
2003-09-24 | E-GEOD-678 | biostudies-arrayexpress
UnknownRandomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma.
Not available
S-EPMC5569691 | biostudies-literature
UnknownSynergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing.
Not available
S-EPMC2910058 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of human cell lines with oestrogen receptor (ER), the E2F transcription factor 4 (E2F4),
The Goal of the experiment was to validate the predicted regulatory modules identified by an algorithm.For this we took advantage of the the genome-wide location analysis technique (or ?ChIP/chip?). We selected modules predicted to be bound by the estrogen receptor (ER), the E2F transcription factor...
ORGANISM(S): Homo sapiens 
2006-05-01 | E-MEXP-471 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 23 human nevi with a pool of primary cutaneous melanoma
Genomic profiles comparing 23 nevi with a pool of primary cutaneous melanoma
ORGANISM(S): Homo sapiens 
2009-04-16 | E-TABM-3 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cohort of human cutaneous primary melanomas associated with a distant metastasis free survival
Identification of genomic characteristics in a cohorte of human cutaneous primary melanoma associated with a distant metastasis free survival.
ORGANISM(S): Homo sapiens 
2007-04-01 | E-TABM-1 | biostudies-arrayexpress
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