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MetabolomicsBenchmark datasets for 3D MALDI- and DESI-Imaging Mass Spectrometry
Three-dimensional imaging mass spectrometry (3D imaging MS) is a technique of analytical chemistry for 3D molecular analysis of a tissue specimen, entire organ, or microbial colonies on an agar plate. 3D imaging MS has unique advantages over existing 3D imaging techniques, offers novel perspectives ...
2016-07-27 | MTBLS176 | MetaboLights
Metabolomics3D DESI mass spectrometry imaging of 51 serial sections from a human liver metastasis
51 serial sections from a single human liver metastasis are made available in this dataset. Four neighbouring sections were placed on a single slide and analysed together. The tissue sections were analysed by desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) according to the pr...
2016-04-28 | MTBLS282 | MetaboLights
Metabolomics3D DESI mass spectrometry imaging of 52 serial sections from a human colorectal adenocarcinoma
Fifty-two serial sections from a single human adenocarcinama are made available in this dataset. Four neighbouring sections were placed on a single slide and analysed together. The tissue sections were analysed by desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) according to t...
2017-03-21 | MTBLS415 | MetaboLights
UnknownAllogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease.
Not available
S-EPMC4872017 | biostudies-literature
UnknownHER2 Gene Amplification Testing by Fluorescent In Situ Hybridization (FISH): Comparison of the ASCO-College of American Pathologists Guidelines With FISH Scores Used for Enrollment in Breast Cancer International Research Group Clinical Trials.
Not available
S-EPMC5074347 | biostudies-literature
UnknownPatterns and Life Course Determinants of Black-White Disparities in Biological Age Acceleration: A Decomposition Analysis.
Not available
S-EPMC10842850 | biostudies-literature
GenomicsBAF250a regulates nucleosome occupancy and histone modification in priming embryonic stem cell differentiation
BAF complex is one major group of chromatin remodeling factors in mammals. However, how BAF regulated nucleosomes and other histone modifications is not clear. Here we delete BAF250a, a major component in esBAF to study the nucleosome and histone changes in ESCs. We find that deletion of BAF250a lea...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-59082 | biostudies-arrayexpress
ProteomicsStructural basis of paralog-specific KDM2A/B nucleosome recognition
The nucleosome acidic patch is a major interaction hub for chromatin, providing a platform for enzymes to dock and orient for nucleosome-targeted activities. In order to define the molecular basis of acidic patch recognition proteome-wide, we performed an amino acid resolution acidic patch interacto...
ORGANISM(S): Homo sapiens (Human) 
2023-02-14 | PXD032791 | Pride
Nucleosome Demethylase Kdm2b Jmjc Chromatin Acidic patch Kdm2a 
UnknownCommunity-Level Factors Associated With Racial And Ethnic Disparities In COVID-19 Rates In Massachusetts.
Not available
S-EPMC8928571 | biostudies-literature
ProteomicsPost-translational modification of H2B C-terminal helix regulates nucleosome binding and chromatin signaling
Histone H2B contains a highly conserved C-terminal (H2B C) helix that has been implicated in chromatin interactions and dynamics. The H2B C helix is positioned adjacent to a major site of nucleosome interactions called the acidic patch. Despite individual structural studies highlighting interactions...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD063304 | Pride
Nucleosomes Protein-protein interactions 
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