Sort   by:  
 Page size 
GenomicsCpG islands recruit a histone H3 lysine 36 demethylase [Illumina sequencing data]
Eukaryotic gene expression profiles are largely defined by transcription factors that recognize specific DNA sequences in gene regulatory regions and impact RNA polymerase recruitment and transcription. In addition to specific core promoter regulatory elements, up to 70% of genes in higher eukaryote...
ORGANISM(S): Mus musculus 
2010-04-27 | E-GEOD-18588 | biostudies-arrayexpress
ProteomicsStructural basis of paralog-specific KDM2A/B nucleosome recognition
The nucleosome acidic patch is a major interaction hub for chromatin, providing a platform for enzymes to dock and orient for nucleosome-targeted activities. In order to define the molecular basis of acidic patch recognition proteome-wide, we performed an amino acid resolution acidic patch interacto...
ORGANISM(S): Homo sapiens (Human) 
2023-02-14 | PXD032791 | Pride
Nucleosome Demethylase Kdm2b Jmjc Chromatin Acidic patch Kdm2a 
TranscriptomicsCpG islands recruit a histone H3 lysine 36 demethylase [Agilent data]
Transcription factors that bind small DNA motifs embedded in promoters play a central role in controlling gene expression. However, in addition to these elements, up to 70% of genes in higher eukaryotes also have high levels of non-methylated cytosine/guanine base pairs (CpGs) surrounding promoters ...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21201 | biostudies-arrayexpress
GenomicsTranscriptome analysis of histone demethylase Kdm2a knockout in mouse embryonic stem cells
Transcriptome analysis of histone demethylase Kdm2a knockout in mouse embryonic stem cells
PRJNA481310 | ENA
GenomicsTumor Cell Clustering Enhances Metastatic Competence by Regulating the H3K36 Histone Demethylase KDM2A
Tumor Cell Clustering Enhances Metastatic Competence by Regulating the H3K36 Histone Demethylase KDM2A
PRJNA1402981 | ENA
TranscriptomicsTranscriptome analysis of histone demethylase Kdm2a knockout in mouse embryonic stem cells
H3K36 methylation plays an important role in gene regulation. The role of H3K36 demethylase Kdm2b has been well studied. However, the role of Kdm2a in embryonic stem cells are still unkonwn. To study the function of Kdm2a in embryonic stem cells. We used CRISPR-gRNA system to knockout Kdm2a. We anal...
ORGANISM(S): Mus musculus 
2019-08-20 | GSE117148 | GEO
GenomicsCpG islands recruit a histone H3 lysine 36 demethylase
This SuperSeries is composed of the following subset Series: GSE18588: CpG islands recruit a histone H3 lysine 36 demethylase [Illumina sequencing data] GSE21201: CpG islands recruit a histone H3 lysine 36 demethylase [Agilent data] Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-21202 | biostudies-arrayexpress
UnknownKDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.
Not available
S-EPMC3859406 | biostudies-literature
GenomicsTumor Cell Clustering Enhances Metastatic Competence by Regulating the H3K36 Histone Demethylase KDM2A [ChIP-Seq]
Tumor Cell Clustering Enhances Metastatic Competence by Regulating the H3K36 Histone Demethylase KDM2A [ChIP-Seq]
PRJNA1404144 | ENA
GenomicsThe Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling during Neurodevelopment [ChIP-seq]
The Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling during Neurodevelopment [ChIP-seq]
PRJNA956291 | ENA
Sort   by:  
 Page size