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TranscriptomicsCharacterization of anaerobic catabolism of p-coumarate in Rhodopseudomonas palustris
To address the question of how photosynthetic bacterium Rhodopseudomonas palustris metabolize lignin derived compound p-coumarate, transcriptomics and quantitative proteomics were combined to characterize gene expression profiles at both the mRNA level and protein level in Rhodopseudomonas palustris...
ORGANISM(S): Rhodopseudomonas palustris 
2008-05-07 | E-GEOD-6221 | biostudies-arrayexpress
TranscriptomicsHuman AoSMCs stimulated by viable P. gingivalis
Porphyromonas gingivalis is a gram-negative bacterium that causes destructive chronic periodontitis. In addition, this bacterium is also involved in the development of cardiovascular disease. The aim of this study was to investigate the effects of P. gingivalis infection on gene and protein expressi...
ORGANISM(S): Homo sapiens 
2013-11-17 | E-MTAB-1922 | biostudies-arrayexpress
TranscriptomicsIntegrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and subsequent gamete fertilisation in mosquitoes is essential for the spreading of the disease. The molecular processes orchestrating these transitions are far from fully understood. Here we report the first transcr...
ORGANISM(S): Plasmodium falciparum 
2016-06-28 | E-GEOD-75795 | biostudies-arrayexpress
ProteomicsThe previously uncharacterized YlxR (RnpM) protein modulates the activity of ribonuclease P
Even though Bacillus subtilis is one of the most studied organisms, no function has been identified for about 20% of its proteins. Among these unknown proteins are several RNA- and ribosome-binding proteins suggesting that they exert functions in cellular information processing. In this work, we hav...
ORGANISM(S): Bacillus subtilis 
2024-06-16 | PXD043900 | Pride
Bacillus subtilis Protein-rna crosslinking 
TranscriptomicsTranscription profiling of colon, ileum, jejunum and liver from wild type and hepatic cytochrome P-450 reductase null mice treated with quercetin to identify differential transcriptional responses to quercetin.
This SuperSeries is composed of the following subset Series: GSE4256: Colon transcriptional response to quercetin in WT and POR-null mice; GSE4257: Ileum transcriptional response to quercetin in WT and POR-null mice; GSE4258: Jejunum transcriptional response to quercetin in WT and POR-null mice; GSE...
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-4262 | biostudies-arrayexpress
TranscriptomicsCyp3a/Mpr2/Mdr1a/1b ko mice
Impact of CYP3A and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir
ORGANISM(S): Mus musculus 
2010-12-12 | E-MTAB-193 | biostudies-arrayexpress
TranscriptomicsAPEX-seq of time course of P-body and Stress Granule transcriptomes during stress
The regulation of cytosolic mRNAs during and after stress occurs through the formation of distinct membraneless organelles. However, the compositional and functional dynamics of these structures throughout the stress response remain poorly understood. Here, we combine APEX2-mediated proximity labell...
ORGANISM(S): Homo sapiens 
2025-12-01 | E-MTAB-14668 | biostudies-arrayexpress
TranscriptomicsMixed Culture Gene Expression of E. coli and Pseudomonas aeruginosa grown on defined media with N-acetyl glucosamine
Transcriptional profiles of Escherichia coli MG1655 in mixed culture with Pseudomonas aeruginosa PAO1 showed a number of E. coli genes to be upregulated including purA-F and other genes associated with purine synthesis. In contrast, genes associated with pyrimidine synthesis were unaffected. Competi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-11-29 | E-GEOD-26932 | biostudies-arrayexpress
TranscriptomicsA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B mono-ubiquitylation to regulate transcript elongation in fission yeast
Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification within transcribed regions, but it remains uncertain how these modifications influence, or are influenced by, properties of the elongation complex. Here we establish an intimate link betw...
ORGANISM(S): Schizosaccharomyces pombe 
2012-12-01 | E-GEOD-31070 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of muscle gene expression in response to an intense cycling exercise. Effect of two protein-leucine enriched diets
Protein-leucine supplement ingestion following strenuous endurance exercise accentuates skeletal-muscle protein synthesis and adaptive molecular responses, but the underlying transcriptome is uncharacterized. In a randomized single-blind triple-crossover design, 12 trained men completed 100 min of h...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-44818 | biostudies-arrayexpress
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