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TranscriptomicsTranscriptome profiling of Saccharomyces cerevisiae during a transition from fermentative to glycerol-based respiratory growth reveals extensive metabolic and structural remodeling.
Transcriptome analyses using a wild-type strain of Saccharomyces cerevisiae were performed to assess the overall pattern of gene expression during the transition from glucose-based fermentative to glycerol-based respiratory growth. These experiments revealed a complex suite of metabolic and structur...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-26 | E-GEOD-29529 | biostudies-arrayexpress
MetabolomicsQuantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome

INTRODUCTION: Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple metabolomics studies have proposed predictive biomarkers of infection severity and outcome. Whilst some trends have emerged, the findings remain intangible and uninformative when it comes to n...

2024-04-23 | MTBLS7429 | MetaboLights
UnknownKu is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.
Not available
S-EPMC2859099 | biostudies-literature
TranscriptomicsHCC Gene Expression Profile
The variability in the prognosis of hepatocellular carcinoma (HCC) patients suggests that HCC may comprise several distinctive biological phenotypes. These phenotypes may result from different neoplastic pathways during the tumorigenesis and/or from a different cell of origin. Here we address if the...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4024 | biostudies-arrayexpress
TranscriptomicsThe YJR127C/ZMS1 gene product is involved in glycerol-based respiratory growth of the yeast Saccharomyces cerevisiae.
A putative yeast mitochondrial upstream activating sequence (UAS) was used in a one-hybrid screening procedure that identified the YJR127C ORF on chromosome X. This gene was previously designated ZMS1 and is listed as a transcription factor on the SGD website. Real time RT-PCR assays showed that exp...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-26 | E-GEOD-29530 | biostudies-arrayexpress
TranscriptomicsCells with features of totipotency derived from human ESC and iPSC by transient BMP4 exposure
Human pluripotent stem cells (hPSC) exposed to BMP4 (B) and inhibitors of ACTIVIN signaling (A83-01; A) and FGF2 (PD173074; P) in absence of FGF2 (BAP conditions) differentiate into colonies primarily comprised of trophoblast. In an attempt to isolate trophoblast stem cells, colonies of hESC were ex...
ORGANISM(S): Homo sapiens 
2015-06-11 | E-GEOD-62065 | biostudies-arrayexpress
TranscriptomicsLIF-Dependent, Pluripotent Stem Cells Established from Inner Cell Mass of Porcine Embryos
The pig is important for agriculture and as an animal model in human and veterinary medicine, yet, despite over 20 years of effort, it has proved a difficult species from which to generate pluripotent stem cells analogous to those derived from mouse embryos. Here we report the production of LIF-depe...
ORGANISM(S): Sus scrofa 
2011-12-02 | E-GEOD-26369 | biostudies-arrayexpress
ProteomicsShotgun Proteomics of BN-PAGE-Resolved Chloroplasts
Blue Native-PAGE resolves protein complexes in their native state. When coupled with immunoblotting, it can be used to identify the presence of high molecular weight complexes at high resolution for any protein, given a suitable antibody. To identify proteins in high molecular weight complexes on a ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-12-23 | PXD003162 | Pride
Oligomeric state Native gel Protein complex Native molecular weight Chloroplast 
TranscriptomicsMouse Hepatocellular Carcinoma Study
Genetically modified mice have been extensively used for analyzing the molecular events that occur during the tumor development. However, in many cases, if not all, it is uncertain to what extent the mouse models reproduce features observed in the corresponding human conditions. This is due largely ...
ORGANISM(S): Mus musculus 
2004-10-28 | E-GEOD-1897 | biostudies-arrayexpress
UnknownCarbapenemases on the move: it's good to be on ICEs.
Not available
S-EPMC6299553 | biostudies-literature
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