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MetabolomicsQuantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome

INTRODUCTION: Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple metabolomics studies have proposed predictive biomarkers of infection severity and outcome. Whilst some trends have emerged, the findings remain intangible and uninformative when it comes to n...

2024-04-23 | MTBLS7429 | MetaboLights
ProteomicsPlasmodium falciparum GBP2 pulldown
This experiment was conducted to learn about the potential biological roles of P. falciparum GBP2 (PfGBP2), a protein identified as part of the telomeric proteome in the malaria parasite P. falciparum. HA-tagged GBP2 protein was immunoprecipitated from P. falciparum parasites and its interactome wa...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-04-04 | PXD028903 | Pride
Plasmodium Malaria Gbp2 
UnknownArginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Not available
S-EPMC4873382 | biostudies-literature
UnknownDisclosure of clinically actionable genetic variants to thoracic aortic dissection biobank participants.
Not available
S-EPMC7923508 | biostudies-literature
TranscriptomicsGene expression signature reflects differentiation differences rather than telomere maintenance mechanism
A gene expression signature purporting to distinguish between telomerase and ALT immortalization has recently been described (Lafferty-Whyte et al., 2009). This was obtained as the intersection of two independent signatures, one obtained from cell lines and the other from a panel of liposarcomas, w...
ORGANISM(S): Homo sapiens 
2010-03-06 | E-GEOD-20559 | biostudies-arrayexpress
UnknownSurgical gestures as a method to quantify surgical performance and predict patient outcomes.
Not available
S-EPMC9780308 | biostudies-literature
TranscriptomicsIntrinsic differentiation potential of human postnatal MSC, Mab and MAPC reflected in their transcriptome
We have employed whole genome microarray expression profiling to identify genes that characterize different populations of human postnatal stem cells and reflect their potency MSC, Mab and MAPC cultures were established from at least three different donors and their transcriptome was assayed using t...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-GEOD-23131 | biostudies-arrayexpress
TranscriptomicsMolecular phenotyping of multiple mouse strains under metabolic challenge uncovers Elovl2 as a novel regulator of glucose-induced insulin secretion
Defective insulin secretion by pancreatic β cells underlies the development of type 2 diabetes (T2D). High fat diet-fed mice are commonly used to study diabetes progression, but studies are usually limited to a single strain, such as C57Bl/6J. Here, we use a systems biology approach to integrate la...
ORGANISM(S): Mus musculus 
2017-04-28 | E-GEOD-78183 | biostudies-arrayexpress
UnknownInterplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Not available
S-EPMC10810843 | biostudies-literature
TranscriptomicsGBM-Space: Joint Transcriptome and Chromatin Accessibility Profiling of Glioblastoma (10x Genomics - Multiome)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17183 | biostudies-arrayexpress
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