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TranscriptomicsTransforming growth factor-B1 drives differentiation of the embryonic jejunum
Transcription profiling by microarray was performed to pinpoint the roles of transforming growth factor B1 (TGFB1) in embryonic differentiation of the small intestine. An organ culture system in which mouse jejunal rudiments were placed on semipermeable platforms and fed with chemically defined seru...
ORGANISM(S): Mus musculus 
2017-04-03 | E-MTAB-4509 | biostudies-arrayexpress
ProteomicsIntegrated liver-secreted and plasma proteomics approaches identify a predictive model that stratifies MASH in bariatric patients
Background & Aims Obesity is a major risk factor for metabolic associated steatotic liver disease (MASLD) which can progress from metabolic associated steatotic liver (MASL) to metabolic associated steatohepatitis (MASH). There are currently no effective and validated screening tools to stratify obe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD052798 | Pride
Masld Hepatokine Apasha Masl Liver-secreted proteome Metabolic associated steatohepatitis Biomarker Plasma proteomics Mash Nash Nafld 
UnknownTransferability and Reproducibility of the HepaRG CometChip Assay.
Not available
S-EPMC12703573 | biostudies-literature
TranscriptomicsEpigenetic antagonism between Snf5 and Ezh2 during oncogenic transformation
Epigenetic alterations have been increasingly implicated in oncogenesis. Analysis of Drosophila mutants suggests that Polycomb and SWI/SNF complexes can serve antagonistic developmental roles. However, the relevance of this relationship to human disease is unclear. Here we have investigated function...
ORGANISM(S): Mus musculus 
2010-10-19 | E-GEOD-23656 | biostudies-arrayexpress
TranscriptomicsCombined PI3K/mTOR and MEK Inhibition Provides Broad Anti-Tumor Activity in Faithful Murine Cancer Models
Anticancer drug development is an inefficient process, with potential therapeutics demonstrating a high attrition rate due to lack of efficacy in Phase II/III testing. In an effort to develop improved pre-clinical predictors of efficacy, we and others have turned to testing in genetically engineere...
ORGANISM(S): Mus musculus 
2012-08-21 | E-GEOD-35722 | biostudies-arrayexpress
UnknownPopulation pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study.
Not available
S-EPMC10777822 | biostudies-literature
UnknownPost-Translational Modifications Distinguish Amyloid-β Isoforms in Cerebral Amyloid Angiopathy and Alzheimer's Disease.
Not available
S-EPMC12745913 | biostudies-literature
UnknownEggs-posed: revision of Schistosoma mansoni venom allergen-like proteins unveils new genes and offers new insights into egg-host interactions.
Not available
S-EPMC11854430 | biostudies-literature
UnknownLiver Disease and Poor Adherence Limit Hepatitis C Cure: A Real-World Australian Treatment Cohort.
Not available
S-EPMC9883319 | biostudies-literature
TranscriptomicsT cell receptor dependent transformation of mature memory phenotype T cells
A fundamental goal in cancer research is identification of the cell types and signaling pathways capable of initiating and sustaining tumor growth as this has the potential to reveal features that can be exploited therapeutically. Stem and progenitor cells have been implicated in the genesis of s...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-29732 | biostudies-arrayexpress
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