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TranscriptomicsGene expression profiling of mouse bone marrow-derived macrophages (RNA-Seq)
Bone marrow (BM) cells were obtained by flushing the long bones of 8-week old C57BL/6 mice. BM cells were then were plated in macrophage SFM medium (Life Technologies) supplemented with penicillin-streptomycin and CSF-1 (Peprotech, 100 ng/ml) and cultured for one week to allow macrophage differenti...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-58283 | biostudies-arrayexpress
TranscriptomicsAn integrated genomics approach for novel biomarker discovery in squamous cell cervical carcinoma
Detection of copy number dependent gene expression profiles in epithelial tumours has lead to the discovery of genes significant in diagnosis, prognosis and of therapeutic value. We sought to apply the technologies of gene expression profiling and copy number aberration detection by high density oli...
ORGANISM(S): Homo sapiens 
2011-03-05 | E-GEOD-27673 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) isolates
Salmonella enterica serovar Typhimurium (S. Typhimurium) definitive phage type 104 (DT104) has caused significant morbidity and mortality in humans and animals for almost three decades. We have completed the full DNA sequence of one DT104 strain, NCTC13348 and show that the main differences between ...
ORGANISM(S): Salmonella enterica 
2008-09-05 | E-MTAB-20 | biostudies-arrayexpress
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
UnknownUsing structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group.
Not available
S-EPMC7473838 | biostudies-literature
UnknownGenome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.
Not available
S-EPMC6787090 | biostudies-literature
GenomicsGenome-Wide Analysis of Hypodiploid Acute Lymphoblastic Leukemia

Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive form of leukemia characterized by multiple whole chromosomal losses and very poor outcome. Here we report an integrative genomic analysis that identifies multiple subtypes of hypodiploid ALL characterized by variation in the degree o...

phs000341.v1.p1 | EGA
ProteomicsTissue- and plasma-derived exosomal protein biomarkers define multiple human cancers
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of exosomes in 426 human samples from tissue explants (TE), plasma and other bodily fluids. Among traditional exosome markers, CD9, HSPA8, ALIX, HSP90AB1 represent ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-08-17 | PXD018301 | Pride
Exosomes  extracellular vesicles  proteomics  cancer  liquid biopsy  biomarkers  mass spectrometry  early cancer detection 
UnknownEffects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort.
Not available
S-EPMC11750427 | biostudies-literature
UnknownEffect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: the TACT randomized trial.
Not available
S-EPMC4066975 | biostudies-literature
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