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ProteomicsEffects of PGRMC1 phosphorylation status on MIA PaCa-2 cells
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014716 | Pride
Proteomics Swath Phosphorylation Pancreatic cancer 
TranscriptomicsMYC drives resistance to PI3K/mTOR targeted inhibition (gene expression)
Gene expression signatures were measured after treatment of cells with 50nM BEZ235. Affymetrix HG-U133AV2 expression arrays were performed according to the manufacturer's directions using RNA extracted by Qiagen RNeasy from engineered human cell-lines grown for 72h in the presence of 50nM BEZ235 Res...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25172 | biostudies-arrayexpress
TranscriptomicsMYC drives resistance to PI3K/mTOR targeted inhibition (Sty SNP array)
Genomic copy-number changes were measured using 250K StyI SNP arrays after selection of cells to enrich for resistance to BEZ235. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted using Qiagen DNeasy from engineered human cell-lines. Resulting alteratio...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25170 | biostudies-arrayexpress
TranscriptomicsA constitutively activated form of the p110 beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice
The global gene expression profiles of ventral prostates of wild type mice and p110 beta transgenic mice. normal prostate vs. prostate cancer induced by the overexpression of the active allele of p110 beta
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-21543 | biostudies-arrayexpress
UnknownPolyoma small T antigen triggers cell death via mitotic catastrophe.
Not available
S-EPMC4286542 | biostudies-literature
UnknownMedicago falcata MfSTMIR, an E3 ligase of endoplasmic reticulum-associated degradation, is involved in salt stress response.
Not available
S-EPMC6849540 | biostudies-literature
TranscriptomicsTranscriptome analysis of the newly described centipede Eupolybothrus cavernicolus sp.n.
We compiled the transcriptome by extracting mRNA, reverse transcription and Illumina sequencing, followed by assembly and annotation by comparison with public databases (including; Nr, SwissProt and COG). Quantitative data on the transcription abundance of each putative protein sequence is provided ...
ORGANISM(S): Eupolybothrus sp. PS-2013 
2013-10-28 | E-MTAB-1859 | biostudies-arrayexpress
UnknownTransgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.
Not available
S-EPMC3094993 | biostudies-literature
UnknownSimian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.
Not available
S-EPMC327122 | biostudies-literature
ProteomicsCompare total proteomics profile of PaCa-2 cells using 1D and 2D IDA LC and SWATH analysis
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014789 | Pride
Cancer Proteomics Swath 
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