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ProteomicsA cell competition-based drug screen identifies a novel compound that induces dual c-Myc degradation and p53 activation
BCR-Abl is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for these diseases, they generally do not kill leukemic stem cells. Leukemic stem cells are cancer-initiating cells that comp...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-07 | PXD018812 | Pride
Leukemia C-myc Drug screening Anticancer drug Abl tyrosine kinase Phosphoproteomics Mrna P53 
UnknownActive idiotypic vaccination versus control immunotherapy for follicular lymphoma.
Not available
S-EPMC4039868 | biostudies-literature
GenomicsMarra_DLBCL_validation - samples
miRNA-seq Cohort of 140 Formalin Fixed Paraffin Embedded Diffuse Large B-cell Lymphoma Patient Samples
EGAD00001001073 | EGA
GenomicsMarra_DLBCL_discovery - samples
miRNA-seq Cohort of 92 Fresh Frozen Diffuse Large B-cell Lymphoma Patient Samples
EGAD00001001074 | EGA
GenomicsMarra_DLBCL_centroblast - samples
miRNA-seq Cohort of 15 Benign Centroblasts
EGAD00001001075 | EGA
GenomicsComprehensive miRNA Sequence Analysis Reveals Survival Differences in Diffuse Large B-cell Lymphoma Patients
Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease, with 30-40% of patients failing to achieve complete responses to standard therapy. miRNAs are RNA molecules that attenuate expression of their mRNA targets. To characterize the DLBCL miRNome, we sequenced miRNAs from 92 DLBCL and 15 ben...
EGAS00001001025 | EGA
UnknownNew-onset atrial fibrillation and chronic coronary syndrome in the CLARIFY registry.
Not available
S-EPMC10834159 | biostudies-literature
UnknownMachine learning-enabled maternal risk assessment for women with pre-eclampsia (the PIERS-ML model): a modelling study.
Not available
S-EPMC10983826 | biostudies-literature
UnknownSimvastatin in Critically Ill Patients with Covid-19.
Not available
S-EPMC10755839 | biostudies-literature
UnknownRare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.
Not available
S-EPMC4673986 | biostudies-literature
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