Sort   by:  
 Page size 
UnknownRandomized Phase III Trial Comparing ABVD Plus Radiotherapy With the Stanford V Regimen in Patients With Stages I or II Locally Extensive, Bulky Mediastinal Hodgkin Lymphoma: A Subset Analysis of the North American Intergroup E2496 Trial.
Not available
S-EPMC4451176 | biostudies-literature
ProteomicsProlyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer
Protein hydroxylation extensively regulates cellular signaling by affecting protein stability, protein-protein interaction and protein activity, and its dysregulation contributes to the pathogenesis of various diseases including cancers. However, because of the transient nature of the enzyme-substra...
ORGANISM(S): Homo sapiens (Human) 
2020-10-06 | PXD015773 | Pride
Hydroxylation Ptm Breast cancer 
ProteomicsDepletion of Mitochondrial Methionine Adenosyltransferase α1 Triggers Mitochondrial Dysfunction in Alcohol-Associated Liver Disease
Mitochondrial MATα1 is selectively depleted in alcohol-associated liver disease through a mechanism that involves the isomerase PIN1 and the kinase CK2. Alcohol activates CK2, which phosphorylates MATα1 at Ser114 facilitating interaction with PIN1, thereby inhibiting its mitochondrial localization. ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-17 | PXD030383 | Pride
Liver Matα1 Mitochondria Alcohol 
ProteomicsSimultaneous proteome localization and turnover analysis of cardiomyocytes under proteasome inhibition
To examine the protein spatial and temporal changes upon carfilzomib-mediated proteasome inhibition in cardiac cells, we produced human iPSC-derived cardiomyocytes using a standard small molecule based protocol. Cardiomyocyte identity was confirmed by morphology, observation of contraction, and the ...
ORGANISM(S): Homo Sapiens (human) 
2023-04-28 | PXD041386 | JPOST Repository
ProteomicsSimultaneous proteome localization and turnover analysis reveals spatiotemporal coordinations of unfolded protein response
The functionality of proteins is dependent on their spatial and temporal distributions, neither of which is directly measured by static protein abundance. Here we report a mass spectrometry-based proteomics workflow and data analysis pipeline, named Simultaneous Proteome Localization and Turnover (...
ORGANISM(S): Homo Sapiens (human) 
2022-12-31 | PXD038054 | JPOST Repository
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
ProteomicsProlyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer
Protein hydroxylation extensively regulates cellular signaling by affecting protein stability, protein-protein interaction and protein activity, and its dysregulation contributes to the pathogenesis of various diseases including cancers. However, because of the transient nature of the enzyme-substra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-02 | MSV000086231 | MassIVE
UnknownAcceptability and Usefulness of a Dyadic, Tailored, Web-Based, Psychosocial and Physical Activity Self-Management Program (TEMPO): A Qualitative Study.
Not available
S-EPMC7650635 | biostudies-literature
UnknownA Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode.
Not available
S-EPMC7667828 | biostudies-literature
UnknownFour-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy.
Not available
S-EPMC10408259 | biostudies-literature
Sort   by:  
 Page size