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GenomicsDNA Methylation in IMR90 cells
DNA methylation was measured by MBD2 enrichment of DNA fragments in IMR90. A statistical model was developed to estimate absolute methylation levels, and compared to whole genome bisulfite sequencing results (Lister, R. et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38679 | biostudies-arrayexpress
UnknownVandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial.
Not available
S-EPMC3675689 | biostudies-literature
ProteomicsMulticolumn Nanoflow Liquid Chromatography System with Accelerated Offline Gradient Generation for Robust and Sensitive Single-Cell Proteome Profiling
Peptide separations that combine high sensitivity, robustness, peak capacity and throughput are essential for extending bottom-up proteomics to smaller samples including single cells. To this end, we have developed a multicolumn nanoLC system with accelerated offline gradient generation. One binary ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049248 | Pride
High throughput Proteomics Lc-ms Storage loop Single cell proteomics Multiple columns 
TranscriptomicsGenome-wide DNA methylation identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity
Previously we have shown that extravillous cytotrophoblast (EVT) outgrowth and migration on a collagen gel explant model were restricted by exposure to decidual natural killer cells (dNK). This study investigates the molecular causes behind this phenomenon. Genome wide DNA methylation of exposed and...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-60885 | biostudies-arrayexpress
TranscriptomicsCultured Cyto and Syncytio-trophoblast samples exposed to varying degrees of hypoxia (methylation)
The mechanisms by which the placenta adapts to exogenous stimuli to create a stable and healthy environment for the growing fetus are not well known. Low oxygen tension and sub-optimal vitamin D levels influence placental function and both are associated with preeclampsia, a condition associated wit...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-41336 | biostudies-arrayexpress
TranscriptomicsCultured Cyto and Syncytio-trophoblast samples exposed to varying degrees of hypoxia
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-41341 | biostudies-arrayexpress
TranscriptomicsCultured Cyto and Syncytio-trophoblast samples exposed to varying degrees of hypoxia (expression)
The mechanisms by which the placenta adapts to exogenous stimuli to create a stable and healthy environment for the growing fetus are not well known. Low oxygen tension and sub-optimal vitamin D levels influence placental function and both are associated with preeclampsia, a condition associated wit...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-41331 | biostudies-arrayexpress
UnknownEffectiveness of occupational therapy-led computer-aided interventions on function among adults with conditions of the hand, wrist, and forearm: A systematic literature review and meta-analysis.
Not available
S-EPMC10683713 | biostudies-literature
UnknownPain Reconceptualisation after Pain Neurophysiology Education in Adults with Chronic Low Back Pain: A Qualitative Study.
Not available
S-EPMC6157134 | biostudies-literature
TranscriptomicsTranscriptomic analysis of the late stages of grapevine (Vitis vinifera cv. Cabernet Sauvignon) berry ripening indicates significant induction of ethylene signaling and flavor pathways in the skin.
Background: Grapevine berry, a nonclimacteric fruit, goes through three developmental stages, the last one called the ripening stage, when the berry changes color and dramatically increases in sugar. Flavors derived from terpenoid and fatty acid metabolism develop at the very end of this ripening st...
ORGANISM(S): Vitis vinifera 
2014-11-01 | E-GEOD-55302 | biostudies-arrayexpress
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