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ProteomicsPeptide toxins that target vertebrate voltage-gated sodium channels underly the painful stings of harvester ants
Harvester ants (genus Pogonomyrmex) are notable for their stings which cause intense, long-lasting pain and other neurotoxic symptoms in vertebrates. Here we show that harvester ant venoms are relatively simple and composed largely of peptide toxins. One class of peptides is primarily responsible fo...
ORGANISM(S): Pogonomyrmex 
2024-06-16 | PXD043773 | Pride
Pain Hymenoptera Venoms Defence Ants 
ProteomicsVenom composition of the ant Tetraponera rufonigra reveals insights into the evolution of dimeric ant venom peptides
The majority of ant species are venomous, and in most lineages, peptide toxins dominate venom composition. Here we investigated the venom of the ant Tetraponera rufonigra (subfamily Pseudomyrmecinae). The major active component, Tr1a, is a homodimeric peptide that is cytolytic, activates mammalian s...
ORGANISM(S): Tetraponera rufonigra 
2026-09-14 | PXD078479 | Pride
Formicidae  pseudomyrmecinae  peptide  sting  pain  homodimer  heterodimer  convergent evolution 
ProteomicsVenom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana
Most species of bee are capable of delivering a defensive sting which is often painful. A solitary lifestyle is the ancestral state of bees and most extant species are solitary, but information on bee venoms comes predominantly from studies on eusocial species. In this study we investigated the veno...
ORGANISM(S): Xylocopa aruana 
2023-03-11 | PXD038183 | Pride
Xylopin Xylopinin Apidae Toxin Apamin Melittin Hymenoptera Carpenter bee 
UnknownCharacteristics of Randomized Clinical Trials in Surgery From 2008 to 2020: A Systematic Review.
Not available
S-EPMC8246313 | biostudies-literature
UnknownRecombination Suppression Drives Expansion of the Drosophila Dot Chromosome.
Not available
S-EPMC12728734 | biostudies-literature
UnknownMultiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
Not available
S-EPMC7615263 | biostudies-literature
UnknownPrenatal Intravenous Magnesium at 30-34 Weeks' Gestation and Neurodevelopmental Outcomes in Offspring: The MAGENTA Randomized Clinical Trial.
Not available
S-EPMC10427942 | biostudies-literature
UnknownPrevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study.
Not available
S-EPMC10005893 | biostudies-literature
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
UnknownClinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.
Not available
S-EPMC9034855 | biostudies-literature
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