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MAM (Microbial-Anti-Inflammatory Molecule) is a 14,5 kDa protein that is one of the best-known effector molecules with anti-inflammatory properties in Faecalibacterium duncaniae, a critical species in the human gut microbiota. Despite its importance, MAM function and molecular features remain poorly...
ORGANISM(S): Faecalibacterium prausnitzii A2-165 
2025-06-30 | PXD057939 | Pride
SF-1, a transcription factor belonging to the nuclear receptor superfamily, has a pivotal role for adrenogonadal development in humans and mice. A constant feature of childhood adrenocortical tumors (ACT) is SF-1 amplification and overexpression. Using an inducible cellular system, here we show that...
ORGANISM(S): Mus musculus 
Faecalibacterium duncaniae A2-165 is a rod-shaped, non-motile, and Extremely Sensitive to Oxygen microorganism, belonging to one of the most abundant genera in the human gut microbiome. A decreased abundance of Faecalibacterium species is correlated to Inflammatory Bowel Diseases (IBDs), highlightin...
ORGANISM(S): Faecalibacterium prausnitzii A2-165 
2026-01-27 | PXD071138 | Pride
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