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UnknownDifferential Immune Checkpoint and Ig-like V-Type Receptor Profiles in COVID-19: Associations with Severity and Treatment.
Not available
S-EPMC9225268 | biostudies-literature
UnknownNuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor.
Not available
S-EPMC3947552 | biostudies-literature
ProteomicsSingle-shot proteome of AML cell lines and AML ex vivo cells upon selinexor treatment
Single-shot proteome analysis of 4 AML cell lines; 2 selinexor sensitive cell lines (GDM-1, MV4-11) and 2 resistant cell lines (NOMO-1 and PL-21) and ex vivo AML cells from 30 patients treated with DMSO (B; before treatment) or 1 uM selinexor (A; after treatment) for 6 hours.
ORGANISM(S): Homo sapiens (Human) 
2022-08-07 | PXD033515 | Pride
Human Lc-msms Aml 
UnknownEffects of whole-body ELECTROMYOSTIMULATION on health and performance: a systematic review.
Not available
S-EPMC6480820 | biostudies-literature
ProteomicsProteogenomic and expression profiling of Marek's disease virus during fully productive replication in the host
Feather follicle epithelium samples were collected from chickens that were infected with Marek's disease virus (MDV). The proteome and phosphoproteome of MDV were then interrogated by high resolution LC-MS.
ORGANISM(S): Gallid Alphaherpesvirus 2 
2023-06-05 | PXD040077 | JPOST Repository
ProteomicsCausal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
The integration of multi-omic data sets can provide unique information about molecular processes in a cell. Despite the development of many tools to extract information from such data sets, there are limited strategies to systematically extract mechanistic hypotheses from them. We here present COSMO...
ORGANISM(S): Homo sapiens (Human) 
2021-02-02 | PXD018218 | Pride
Q exactive hf-x Human Kidney Phosphorylation 
ProteomicsPhosphorylation-depended conformational changes in KAHRP of Palsmodium falciparum
This dataset contains phosphoproteomic data generated to characterize phosphorylation of the knob-associated histidine-rich protein (KAHRP) in Plasmodium falciparum-infected erythrocytes. The study investigates the role of KAHRP phosphorylation in regulating its stage-specific interaction with the e...
ORGANISM(S): Homo sapiens (Human) 
2026-10-12 | PXD083281 | Pride
P. falciparum kahrp ankyrin phosphoproteomics 
MetabolomicsDynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...

2022-12-08 | MTBLS5615 | MetaboLights
ProteomicsSpatial proteomics of selinexor, MK-2206 and combination response in AML cells
In order to characterize the dynamics of proteins between different cellular compartments in response to selinexor (XPO1 inhibitor), MK-2206 (Akt inhibitor) an the combination i AML cells, we treated MV4-11 and PL-21 cells for 6 hours with DMSO, 1 uM selinexor, 1 uM MK-2206 or the combination. Each...
ORGANISM(S): Homo sapiens (Human) 
2022-08-07 | PXD033527 | Pride
Human Spatial proteomics Aml Lc-ms/ms 
ProteomicsPhosphoproteomics analysis of Selinexor response in AML ex vivo patient samples and cell lines
We used mass spectrometry-based proteomics to perform a phosphoproteomics analysis of selinexor-treated ex vivo AML patient samples (n=20) and 4 AML cell lines (PL-21, NOMO-1, GDM-1 and MV4-11). For quantitative phosphoproteomics, we used a tandem mass tag (TMT)-based approach. Conditions for the TM...
ORGANISM(S): Homo sapiens (Human) 
2022-08-07 | PXD017660 | Pride
Lc-msms Selinexor Human Aml 
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