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ProteomicsDirect ionic stress sensing and mitigation by the transcription factor NFAT5
Homeostatic control of intracellular ionic strength is essential for protein, organelle and genome function, yet mechanisms that sense and enable adaptation to ionic stress remain poorly understood in animals. We find that the transcription factor NFAT5 directly senses solution ionic strength using ...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-17 | PXD052591 | Pride
Hypertonic stress Proximity biotinylation Biomolecular condensates Ionic stress Intrinsically disordered protein Nfat5 Tonebp Phase separation 
TranscriptomicsGene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4
The aim of this study is to analyze the change in genome wide expression levels in HAP1 cells upon loss of SMARCB1, SMARCA4 or both these genes together. The SMARCB1 and SMARCA4 genes were the hits from a genome wide screen involving genetrap mutagenesis to find new players that are involved in sen...
ORGANISM(S): Homo sapiens 
2016-08-22 | E-GEOD-75515 | biostudies-arrayexpress
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