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TranscriptomicsEffect of mago nashi depletion on gene expression in Drosophila S2R+ cells
This study was designed to identify changes in gene expression resulting from depletion of Mago nashi (Mago), a core subunit of the exon junction complex. Drosophila S2R+ cells were treated with double-stranded RNA targeting either LacZ or Mago for 6 days. Poly(A)+ RNA was purified from each sample ...
ORGANISM(S): Drosophila melanogaster 
2010-10-20 | E-GEOD-23997 | biostudies-arrayexpress
TranscriptomicsThe exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript
The exon junction complex (EJC) is a highly conserved ribonucleoprotein complex which binds RNAs during splicing and remains associated with them following export to the cytoplasm. While the role of this complex in mRNA localization, translation and degradation has been well characterized, its mecha...
ORGANISM(S): Drosophila melanogaster 
2014-08-14 | E-GEOD-59327 | biostudies-arrayexpress
TranscriptomicsThe exon junction complex controls transposable element activity by ensuring the faithful splicing of the piwi transcript
The exon junction complex (EJC) is a highly conserved ribonucleoprotein complex which binds RNAs at a late stage of the splicing reaction and remains associated following export to the cytoplasm. This complex is involved in several cellular post-transcriptional processes including mRNA localization,...
ORGANISM(S): Drosophila melanogaster 
2014-09-08 | E-GEOD-57710 | biostudies-arrayexpress
ProteomicsMakorin 1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation
Makorins are an evolutionary conserved family of proteins that contain C3H-type zinc finger modules and a RING E3 ubiquitin ligase domain. Previous analysis indicated a maternal role for Makorin 1 (Mkrn1) in Drosophila embryonic patterning and germ cell specification, but the underlying mechanism ha...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-01-29 | PXD011802 | Pride
Polyadenylation Pole plasm Germ cell specification Drosophila Oogenesis Mkrn1 
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