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Kallenberger2014 - CD95L induced apoptosis initiated by caspase-8, CD95 HeLa cells (cis/trans-cis/trans variant) The paper describes a new approach that combines single cell and population data in the same model. The model consists of a large number of single cell models, which are...
2024-09-02 | BIOMD0000000525 | BioModels
Kallenberger2014 - CD95L induced apoptosis initiated by caspase-8, wild-type HeLa cells (cis/trans-cis/trans variant) The paper describes a new approach that combines single cell and population data in the same model. The model consists of a large number of single cell models, whic...
2024-09-02 | BIOMD0000000526 | BioModels
Kallenberger2014 - CD95L induced apoptosis initiated by caspase-8, CD95 HeLa cells (cis/trans variant) The paper describes a new approach that combines single cell and population data in the same model. The model consists of a large number of single cell models, which are fitted to...
2024-09-02 | BIOMD0000000523 | BioModels
Kallenberger2014 - CD95L induced apoptosis initiated by caspase-8, wild-type HeLa cells (cis/trans variant) The paper describes a new approach that combines single cell and population data in the same model. The model consists of a large number of single cell models, which are fitt...
2024-09-02 | BIOMD0000000524 | BioModels
For the MALDI-MSI experiment, we selected 12 different drugs. The drugs were purchased from the LC Laboratories (Woburn, MA; CAS numbers: dabrafenib: 1195765-45-7, dasatinib: 302962-49-8, erlotinib: 183321-74-6, gefitinib: 184475-35-2, imatinib: 152459-95-5, lapatinib: 388082-78-8, pazopanib: 444731...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-06 | PXD016146 | Pride
Male rats from one of four strains (Wistar, AA, HAD or P) were housed individually in standard hanging rodent cages (Ehret, Emmendingen, Germany) on a 12-hour light-dark cycle with lights on at 07:00 a.m.. Animals were provided with food (Sniff, Soest, Germany), tap water, 5, 10 and 20% (v/v) ethano...
ORGANISM(S): Rattus norvegicus 
Microarray analysis has been useful for identifying the targets of many transcription factors. However, gene expression changes in response to transcription factor perturbation reveal both direct transcriptional targets and secondary gene regulation. By integrating RNA interference, gene expression ...
ORGANISM(S): Homo sapiens 
Postnatal neural progenitors of the enteric nervous system are a potential source for future cell replacement therapies of developmental dysplasia like Hirschrpung’s disease. However, little is known about the molecular mechanisms driving the homeostasis and differentiation of this cell pool. In thi...
ORGANISM(S): Mus musculus 
The NOTCH signaling cascade, which is deregulated in T-cell acute lymphoblastic leukemia (T-ALL) and many other human cancers, offers an attractive target for molecular therapy. One approach employs gamma-secretase inhibitors (GSIs) to suppress production of the intracellular form of NOTCH (NICD), ...
ORGANISM(S): Homo sapiens 
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