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TranscriptomicsTranscription profiling of human B lineage chronic lymphocytic leukemia, normal B, and normal T cells treated with rolipram, a PDE4 inhibitor
PDE4 inhibitors, which activate cAMP signaling by reducing cAMP catabolism, are known to induce apoptosis in B lineage chronic lymphocytic leukemia (CLL) cells but not normal human T cells. The explanation for such differential sensitivity remains unknown. Here, we report studies contrasting the res...
ORGANISM(S): Homo sapiens 
2009-03-07 | E-GEOD-13987 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hippocampal slices after NMDA or forskolin-rolipram-0 Mg2+ or bicuculline treatment
Effect of different chemical stimuli (NMDA(N-methyl-D-aspartic acid), forskolin/rolipram/0 Mg, bicuculline) on gene expression after 1 h of stimulation in hippocampal slices
ORGANISM(S): Mus musculus 
2008-06-01 | E-MEXP-1184 | biostudies-arrayexpress
UnknownA multifaceted examination of the action of PDE4 inhibitor rolipram on MMP2/9 reveals therapeutic implications.
Not available
S-EPMC11958756 | biostudies-literature
UnknownRolipram and Electrical Stimulation Synergistically Promote Neuronal Differentiation of Adipose-derived Stromal Cells: an in Vitro Study.
Not available
S-EPMC12408716 | biostudies-literature
UnknownDownregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder.
Not available
S-EPMC3438357 | biostudies-literature
UnknownThe protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway.
Not available
S-EPMC8492710 | biostudies-literature
UnknownProtective effects of rolipram on endotoxic cardiac dysfunction via inhibition of the inflammatory response in cardiac fibroblasts.
Not available
S-EPMC7247226 | biostudies-literature
UnknownPDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer.
Not available
S-EPMC11879692 | biostudies-literature
UnknownThe type IV-specific phosphodiesterase inhibitor rolipram and its effect on hippocampal long-term potentiation and synaptic tagging.
Not available
S-EPMC6729613 | biostudies-literature
UnknownRolipram plays an anti-fibrotic effect in ligamentum flavum fibroblasts by inhibiting the activation of ERK1/2.
Not available
S-EPMC8461931 | biostudies-literature
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