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Unknown"Seeing the balance in the two worlds in which I exist": Latinx trans and nonbinary individuals' experiences of within-culture gender minority stress and resilience.
Not available
S-EPMC11948218 | biostudies-literature
UnknownA human progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans
Not available
S-SCDT-10_1038-S44318-024-00261-8 | biostudies-other
GenomicsPharmacological and genomic profiling identifies NFκB-targeted treatment strategies for mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive malignancy characterized by poor prognosis, underscoring the need for novel therapeutic strategies1. In this study, we employed large-scale pharmacological profiling of 16 pathway inhibitors across more than 100 hematological cell line models to identify n...
EGAS00001000622 | EGA
Genomicsena-DATASET-BCCA-06-12-2013-17:57:13:627-21 - samples
Complete set of bam files associated with study EGAS00001000622
EGAD00001000702 | EGA
UnknownAssociation of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.
Not available
S-EPMC10469654 | biostudies-literature
ProteomicsA novel non-galactosylated tolerogenic antigen-specific vaccine protects against arthritis via VISTA-expressing regulatory T cells in DRB1*04:01 mice
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, cartilage damage and bone erosion. Despite improvements with the introduction of biological disease-modifying anti-rheumatic drugs (DMARDs), RA remains incurable. Advancements in peptide-based vaccination...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD056818 | Pride
Vaccine Arthritis Mice Immune cells 
UnknownSoluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease.
Not available
S-EPMC8247308 | biostudies-literature
TranscriptomicsRNA-seq of SARS-CoV-2-infected human primary hepatocyte-derived spheroids upon interferon a2 and baricitinib treatment
Biological replicates of liver spheroids derived from primary hepatocytes were treated with IFNa2 and/or baricitinib for 24 h and subsequently infected with Sars-CoV-2. The cells were harvested 48 h time after infection. Total RNA was extracted and sequenced with a strand-specific paired end RNA-seq...
ORGANISM(S): Homo sapiens 
2020-11-18 | E-MTAB-9711 | biostudies-arrayexpress
ProteomicsBone marrow-selected antigen specific regulatory B cells
Autoimmunity is often regarded as pathogenic, but this view has gradually shifted over time. Based on insights from thymus selection, T cells are now known to be selected by self-antigens and positive selection in the thymus medulla leads to regulatory functions. B cells are selected in the bone mar...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-13 | PXD025837 | Pride
Breg Lc-ms/ms Facs Mouse 
ProteomicsA peptide-based tolerizing vaccine against autoimmune arthritis directly interacting with antigen-specific T cells
A longstanding goal has been to find an antigen-specific preventive therapy, i.e., a vaccine, for autoimmune diseases. Major hindrances have so far been to select natural regulatory antigen targets and side-effects induced by clustering the T cell receptor (TCR) or activating the costimulatory signa...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-15 | PXD034792 | Pride
Autoimmune arthritis Arthritis Antigen-specific t cells Vaccine 
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