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ProteomicsEnvironmental stress affects the activity of metabolic and growth factor signaling networks and induces autophagy markers in breast cancer cell lines
The breast cancer cell line MCF7 was exposed to RT comditions for 15min, 2h or left in the incubator. Cells were harvested and lyzed. Samples were digested with trypsin and subjected to phosphoenrichment usin TiO2. Phosphopeptides were run in a LTQ-Orbitrap-XL. 4 biological replicates per condition ...
ORGANISM(S): Homo sapiens (Human) 
2014-04-11 | PXD000472 | Pride
Label free Mcf7 Room temperature exposition Tio2 phosphoenrichment 
TranscriptomicsIdentification of differentially regulated genes in Populus deltoides subjected to copper stress using 4.6K cDNA arrays
cDNA macroarray expression profiling was carried out in poplar roots in order to identify genes regulated in response to exposition to copper stress. For this purpose, plants of a Populus deltoides clone grown in a hydroponic system during four weeks were incubated in a nutrient solution (Hoagland'...
ORGANISM(S): Populus deltoides 
2010-05-06 | E-GEOD-9748 | biostudies-arrayexpress
UnknownDevelopment of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects.
Not available
S-EPMC5834504 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis treated with of two cadmium concentrations on leaves and roots at three different times
Dynamic of the Arabidopsis thaliana transcriptome following a cadmium exposition.
The goal of the project is to developp a global approach without a priori in order to identify the key players involved in response to cadmium: signalisation and mechanisms of detoxification in the model plant Arab...
ORGANISM(S): Arabidopsis thaliana 
2005-12-01 | E-MEXP-416 | biostudies-arrayexpress
UnknownCo-flow injection for serial crystallography at X-ray free-electron lasers.
Not available
S-EPMC8805165 | biostudies-literature
TranscriptomicsCampylobacter jejuni transcriptomic response to benzylisothiocyanate
Campylobacter jejuni is a widespread pathogen responsible for most of the food-borne gastrointestinal diseases in Europe. For pathogen control in the food industry, the use of natural antimicrobial molecules is a promising strategy to avoid antibiotic treatments. Isothiocyanates are natural antimicr...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 
2013-09-19 | E-GEOD-45823 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human monocytes and monocyte-derived macrophages infected with Coxiella burnetii and incubated with apoptotic or necrotic lymphocytes
Q fever is due to Coxiella burnetii, an obligate intracellular bacterium. We investigated the mechanism of establishment of chronic form of the Q fever that mainlym anifested by endocarditis. We showed that patients with acute Q fever and valvulopathy, who have the higher risk to develop an endocar...
ORGANISM(S): Homo sapiens 
2008-10-09 | E-MEXP-1289 | biostudies-arrayexpress
MetabolomicsChemical Diversity and Classification of Secondary Metabolites in Nine Bryophyte Species

The central aim in ecometabolomics and chemical ecology is to pinpoint chemical features that explain molecular functioning. The greatest challenge is the identification of compounds due to the lack of constitutive reference spectra, the large number of completely unknown compounds, and bioinform...

2019-12-31 | MTBLS709 | MetaboLights
ProteomicsFirst identification of a large set of serine hydrolases by activity-based protein profiling in dibutyl phthalate-exposed zebrafish larvae
Despite the involvement of several serine hydrolases (SHs) in the metabolism of xenobiotics such as dibutyl phthalate (DBP), no study has focused on mapping this enzyme class in zebrafish, a model organism frequently used in ecotoxicology. Here, we survey and identify active SHs in zebrafish larvae ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-03-11 | PXD038229 | Pride
Proteomics Zebrafish larvae Activity-based protein profiling Serine hydrolases Dibutyl phthalate 
ProteomicsSPATEs promote the survival of Shigella to the plasma complement system upon local hemorrhage and bacteremia
"Shigella spp. are the causative agents of shigellosis, which remains a major cause of death in children under the age of five. Shigellosis is marked by fever and leads to hemorrhagic diarrhea; Shigella bacteremia are reported in more severe cases. These clinical features strongly suggest that Shige...
ORGANISM(S): Homo sapiens (Human) 
2024-08-27 | PXD048033 | Pride
Haemorrhage Complement system Bacteremia Spate Shigella 
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