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TranscriptomicsCRISPR screen exploring resistance to AKTi (Capivasertib) in ER+ Breast Cancer in MCF7, T47D and CAMA-1 cell lines
A genome-wide CRISPR-Cas9 knockout screen was performed in the breast cancer cell lines T47D, MCF7, and CAMA-1 to identify genes modulating sensitivity and resistance to capivasertib, a selective AKT inhibitor. Cells were transduced with a CRISPR library, followed by treatment with capivasertib or v...
ORGANISM(S): Homo sapiens 
2026-05-25 | E-MTAB-16438 | biostudies-arrayexpress
TranscriptomicsExpression data from Arabidopsis gapcp mutant
Glycolytic Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) catalyzes the conversion of glyceraldehyde 3-phospate to 1,3-bisphosphoglycerate by coupling with the reduction of NAD+ to NADH. Both cytosolic and plastidial isoforms of GAPDH has been described but the in vivo functions of the plastidial ...
ORGANISM(S): Arabidopsis thaliana 
2009-02-21 | E-GEOD-14765 | biostudies-arrayexpress
TranscriptomicsExpression data from Arabidopsis gapcp mutant treated with ABA
Glycolytic Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) catalyzes the conversion of glyceraldehyde 3-phospate to 1,3-bisphosphoglycerate by coupling with the reduction of NAD+ to NADH. We generated mutants of the Arabidopsis plastidial GAPDH isoforms (At1g79530, At1g16300; GAPCp1, GAPCp2). gapcp...
ORGANISM(S): Arabidopsis thaliana 
2010-05-28 | E-GEOD-21765 | biostudies-arrayexpress
UnknownElevated neutrophil extracellular traps by HBV-mediated S100A9-TLR4/RAGE-ROS cascade facilitate the growth and metastasis of hepatocellular carcinoma.
Not available
S-EPMC9926958 | biostudies-literature
UnknownSLC25A39 identified as a key regulator of hepatocellular carcinoma progression through the mitochondrial ROS-cytochrome c-caspase signaling axis.
Not available
S-EPMC12751652 | biostudies-literature
UnknownImpact of inflammation on anemia in children: a cross-sectional study.
Not available
S-EPMC11967137 | biostudies-literature
UnknownOxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G.
Not available
S-EPMC5483177 | biostudies-literature
UnknownPINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Not available
S-EPMC6735223 | biostudies-literature
ProteomicsProteomics of tumor and serum samples from isocitrate dehydrogenase-wildtype glioblastoma patients: is the detoxification of reactive oxygen species associated with shorter survival?
Proteomics has been little used for the identification of novel prognostic and/or therapeutic markers in isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GB). In this study, we analyzed 50 tumor and 30 serum samples from short- and long-term survivors of IDH-wildtype GB (STS and LTS, respective...
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD045714 | Pride
Dia-ms  tims-tof-pro  glioblastoma  survival 
UnknownA design for an efficient functional panel that determines platelet exhaustion levels to differentiate responder and non-responder ITP patients.
Not available
S-EPMC12578879 | biostudies-literature
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