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MetabolomicsAberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Xenograft assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS730 | MetaboLights
MetabolomicsAberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Stem cell and cell line assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS4708 | MetaboLights
MetabolomicsA machine learning model for the prediction and verification of the protective intestinal microbiota-derived L-valine in sepsis

The intestinal microflora and metabolites produced by these microbes serve as important regulators of the development of sepsis. Accordingly, this study was designed to systematically explore the relationships between the regulation of septicemia and both the intestinal flora and fecal metabolite...

2023-07-28 | MTBLS7866 | MetaboLights
ProteomicsIdentification of an RNA sponge that controls the levels, processing and efficacy of the RoxS riboregulator of central metabolism in B. subtilis
Only a few small regulatory RNAs (sRNAs) have been characterized in B. subtilis, the paradigm of Gram-positive bacteria, and one of the major challenges is target identification. Here we use global in vivo RNA psoralen cross-linking to identify RNA-RNA partners in Bacillus subtilis. Two sRNAs, RoxS ...
ORGANISM(S): Bacteria Bacillus subtilis 
2021-09-08 | PXD015051 | Pride
Metabolism Roxs Rosa Bacillus subtilis Rnas 
Transcriptomicsaffy_duplicature_lyon_rose. Double flower phenomenon: Control of petal number in roses
affy_duplicature_lyon_rose. The objective is to identify the genes involved in petal doubling in rose. In this study we are using two rosa gallica genotypes: wild-type (simple flower rose) and Cardinal de Richelieu (double flower rose), and two rosa hybrida genotypes : Souvenir de la Malmaison, whic...
ORGANISM(S): Rosa hybrid cultivar 
2011-08-31 | E-GEOD-18353 | biostudies-arrayexpress
Transcriptomicsaffy_rose_2012_06: RhDiF1 knockdown
affy_rose_2012_06 - affy_rose_2012_06 - - Study of rose perfume by comparing a wild-tpe rose with one in which the expression of a scent gene has been altered.-Study of rose perfume by comparing a wild-tpe rose with one in which the expression of a scent gene has been altered. 8 arrays - rose; norma...
ORGANISM(S): Rosa chinensis 
2013-09-12 | E-GEOD-45236 | biostudies-arrayexpress
TranscriptomicsTranscriptome inheritance of a citrus somatic hybrid
The main objective of the present study was to analyze whether the novel phenotype of this complex three-way tetraploid interspecific hybrid, displaying mixed dominant, codominant and transgressive traits is associated with non additive expression of the two diploid parental genomes. Keywords: Comp...
ORGANISM(S): Citrus limon 
2010-06-21 | E-GEOD-18386 | biostudies-arrayexpress
UnknownBarcoding Eophila crodabepis sp. nov. (Annelida, Oligochaeta, Lumbricidae), a Large Stripy Earthworm from Alpine Foothills of Northeastern Italy Similar to Eophila tellinii (Rosa, 1888).
Not available
S-EPMC4809493 | biostudies-literature
UnknownBiomolecular insights into North African-related ancestry, mobility and diet in eleventh-century Al-Andalus.
Not available
S-EPMC8438022 | biostudies-literature
TranscriptomicsHost microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses
In this study, we performed a miRNA global profiling in human lung epithelial cells (A549) infected by two different subtypes of human influenza A viruses (H1N1 and H3N2). A549 cells were either mock-infected or infected at a multiplicity of infection (MOI) of 1 with H1N1 or H3N2 viruses, and total ...
ORGANISM(S): Homo sapiens 
2013-04-03 | E-GEOD-42003 | biostudies-arrayexpress
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