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ProteomicsMolecular surface mimicry enables CRBN to target G3BP2 for degradation
Molecular glue degraders (MGDs) are small molecule compounds that repurpose the ubiquitin-proteasome system to induce degradation of challenging therapeutic targets. Thalidomide-analogs are clinically effective MGDs that bind cereblon (CRBN), a substrate receptor of the Cullin-4/RING E3 ubiquitin li...
ORGANISM(S): Homo sapiens (Human) 
2026-01-14 | PXD064243 | Pride
Targeted protein degradation Monte rosa therapeutics G3bp2 Crbn Molecular glue 
UnknownA taxogenomic view of the genus <i>Torulaspora</i>: an expansion from ten to twenty-two species.
Not available
S-EPMC12308288 | biostudies-literature
UnknownRegional patterns of δ 13C and δ 15N for European common cuttlefish (Sepia officinalis) throughout the Northeast Atlantic Ocean and Mediterranean Sea.
Not available
S-EPMC8437227 | biostudies-literature
GenomicsRGA binding sites in Arabidopsis thaliana seedlings
DELLA proteins act as hubs that relay environmental information to the multiple transcriptional circuits that control growth and development through physical interaction with transcription factors from different families. We have analyzed the presence of one DELLA protein at the Arabidopsis genome b...
ORGANISM(S): Arabidopsis thaliana 
2015-07-23 | E-GEOD-59187 | biostudies-arrayexpress
TranscriptomicsExpression data of Arabidopsis seedlings in response to ARR1 or cytokinins, in the presence and absence of DELLA proteins
DELLA proteins interact with ARR1 and modulate its activity. We have investigated the effect of DELLA proteins on transcriptional regulation by ARR1 A dominant hyperactive allele of ARR1 was induced with dexamethasone in seedlings preincubated with paclobutrazol (allowing DELLA acummulation) or pacl...
ORGANISM(S): Arabidopsis thaliana 
2015-06-13 | E-GEOD-69828 | biostudies-arrayexpress
UnknownLinkage map construction and QTL mapping for morphological traits in Ipomoea trifida, a diploid sweetpotato relative.
Not available
S-EPMC12445336 | biostudies-literature
UnknownImpact of Antihypertensive Medication Changes After Renal Denervation Among Different Patient Groups: SPYRAL HTN-ON MED.
Not available
S-EPMC11025607 | biostudies-literature
UnknownAdapting Agriculture to Climate Change: A Synopsis of Coordinated National Crop Wild Relative Seed Collecting Programs across Five Continents.
Not available
S-EPMC9319254 | biostudies-literature
UnknownDetection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.
Not available
S-EPMC7724284 | biostudies-literature
UnknownEcological mechanisms explaining interactions within plant-hummingbird networks: morphological matching increases towards lower latitudes.
Not available
S-EPMC7126064 | biostudies-literature
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